SCHEMBL4328899

SCHEMBL4328899

CC1(C)[CH]C1c1ccccc1

nearest known ligand 0.44

Predicted protein targets (top 10)

geneUniProtsupporting neighboursconfidence
MAOA P21397 9/20 0.44
MAOB P27338 9/20 0.44
KDM1A O60341 8/20 0.44
CHRNA7 P36544 1/20 0.39
ALDH1A1 P00352 1/20 0.36
TRPA1 O75762 1/20 0.35
TSHR P16473 1/20 0.35
MEN1 O00255 1/20 0.34
CYP2C19 P33261 1/20 0.34
KMT2A Q03164 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8782024 0.72 TSHR (0.35) MAOAMAOBKDM1ATSHRMEN1
SCHEMBL4337871 0.72 KDM1A (0.44) MAOAMAOBKDM1AALDH1A1TSHR
SCHEMBL3992251 0.72 KDM1A (0.36) MAOAMAOBKDM1ACHRNA7ALDH1A1
SCHEMBL10847543 0.70 CA1 (0.50) MAOAMAOBKDM1AALDH1A1
SCHEMBL9842729 0.70 TSHR (0.42) ALDH1A1TSHRKMT2A
SCHEMBL30312019 0.69 KDM1A (0.46) MAOAMAOBKDM1ACHRNA7ALDH1A1
SCHEMBL23396586 0.68 KDM1A (0.37) MAOAMAOBKDM1ACHRNA7
SCHEMBL17821191 0.65 CYP3A4 (0.48) MAOAMAOBKDM1ACHRNA7TSHR
SCHEMBL16377487 0.65 CYP3A4 (0.48) MAOAMAOBKDM1ACHRNA7TSHR
SCHEMBL4331068 0.65 KDM1A (0.67) MAOAMAOBKDM1A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 31 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-4493844-A Insecticidal 2,2'-bridged(1,1'-biphenyl)-3-ylmethyl carboxamides FMC CORPORATION (US) 1985-01-15 US claimed
US-4487778-A Insecticidal esters derived from benzocycloalkane-thiophenemethyl compounds FMC CORPORATION (US) 1984-12-11 US claimed
CN-103373911-B Single fluoro cyclopropanes compound and its preparation method and application 中国科学院上海有机化学研究所 2016-12-14 CN disclosed
CN-101817784-B Ethylene derivatives and pesticides containing said derivatives NISSAN CHEMICAL INDUSTRIES CO., LTD. (JP) 2012-02-01 CN disclosed
CN-101817784-A Ethene derivatives and the pesticides that contains this derivative NISSAN CHEMICAL IND LTD 2010-09-01 CN disclosed
US-7566683-B2 Ethylene derivatives and pesticides containing said derivatives NISSAN CHEMICAL INDUSTRIES, LTD. (JP) 2009-07-28 US disclosed
WO-2007100161-A1 METHOD FOR PREFERENTIAL PRODUCTION OF GEOMETRIC ISOMERS AND ISOLATION METHOD NISSAN CHEMICAL INDUSTRIES, LTD. (JP) 2007-09-07 WO disclosed
US-20070049495-A1 Ethylene derivatives and pesticides containing said derivatives NISSAN CHEMICAL INDUSTRIES, LTD. (JP) 2007-03-01 US disclosed
US-7037880-B2 Ethylene derivatives and pesticides containing said derivatives NISSAN CHEMICAL INDUSTRIES, LTD. (JP) 2006-05-02 US disclosed
CN-1763003-A Ethylene derivatives and pesticides containing the same NISSAN CHEMICAL IND LTD (JP) 2006-04-26 CN disclosed
CN-1227229-C Ethylene derivatives and pesticides containing the same NISSAN CHEMICAL IND LTD (JP) 2005-11-16 CN disclosed
CN-1216530-A Ethylene derivatives and pesticides containing the same NISSAN CHEMICAL IND LTD (JP) 1999-05-12 CN disclosed
EP-0913392-A1 ETHYLENE DERIVATIVES AND PEST CONTROLLING AGENTS NISSAN CHEMICAL INDUSTRIES, LIMITED (JP) 1999-05-06 EP disclosed
US-4605748-A INSECTICIDES, MITICIDES FMC CORPORATION (US) 1986-08-12 US disclosed
US-4596892-A 6,7-Dihydro-5H-dibenzo(a,c)cyclohepten-4-methanoamine FMC CORPORATION (US) 1986-06-24 US disclosed
US-4507317-A Acaricidal 2,2'-bridged[1,1'-biphenyl]-3-ylmethyl esters FMC CORPORATION (US) 1985-03-26 US disclosed
US-4493844-A Insecticidal 2,2'-bridged(1,1'-biphenyl)-3-ylmethyl carboxamides FMC CORPORATION (US) 1985-01-15 US disclosed
US-4487778-A Insecticidal esters derived from benzocycloalkane-thiophenemethyl compounds FMC CORPORATION (US) 1984-12-11 US disclosed
US-4451484-A ALSO MITICIDES FMC CORPORATION (US) 1984-05-29 US disclosed
US-4433182-A Insecticidal 2,2'-bridged[1,1'-biphenyl]-3-ylmethyl esters FMC CORPORATION (US) 1984-02-21 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20070049495-A1 Ethylene derivatives and pesticides containing said derivatives DDT, ECE1, EBPL MAOA 1790/4885MAOB 1141/4885KDM1A 878/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.