Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOB | P27338 | 8/20 | 0.68 |
| ▸ | IDO1 | P14902 | 2/20 | 0.56 |
| ▸ | NR4A2 | P43354 | 2/20 | 0.54 |
| ▸ | MAPT | P10636 | 2/20 | 0.53 |
| ▸ | HTT | P42858 | 1/20 | 0.53 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.53 |
| ▸ | FFAR4 | Q5NUL3 | 2/20 | 0.51 |
| ▸ | POLB | P06746 | 1/20 | 0.51 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.51 |
| ▸ | SLC26A3 | P40879 | 1/20 | 0.51 |
| ▸ | MRGPRX4 | Q96LA9 | 1/20 | 0.50 |
| ▸ | PRKD3 | O94806 | 1/20 | 0.50 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.50 |
| ▸ | CDK7 | P50613 | 1/20 | 0.50 |
| ▸ | JAK3 | P52333 | 1/20 | 0.50 |
| ▸ | TNK2 | Q07912 | 1/20 | 0.50 |
| ▸ | S1PR5 | Q9H228 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4322451 | 0.84 | MAOB (0.62) | MAOBIDO1 | |
| SCHEMBL12879351 | 0.82 | MAOB (0.65) | MAOBIDO1NR4A2MAPTHTT | |
| SCHEMBL3320586 | 0.81 | MAOB (1.00) | MAOBIDO1NR4A2MAPTHTT | |
| SCHEMBL23350560 | 0.81 | MAOB (0.73) | MAOBIDO1NR4A2MAPTHTT | |
| SCHEMBL4319284 | 0.81 | MAOB (0.65) | MAOBIDO1NR4A2 | |
| SCHEMBL1578390 | 0.80 | MAOB (0.57) | MAOBNR4A2MAPTHTTL3MBTL1 | |
| SCHEMBL18164545 | 0.79 | MAOB (0.63) | MAOBNR4A2MAPTHTTL3MBTL1 | |
| SCHEMBL4640143 | 0.79 | MAOB (0.76) | MAOBIDO1NR4A2MAPTHTT | |
| SCHEMBL31172140 | 0.79 | MAOB (0.76) | MAOBIDO1NR4A2MAPTHTT | |
| SCHEMBL28656259 | 0.79 | HTR2A (0.53) | MAOBIDO1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8492588-B2 | Benzyloxy anilide derivatives useful as potassium channel modulators | VALEANT PHARMACEUTICALS INTERNATIONAL (US) | 2013-07-23 | — | — | US | disclosed |
| US-20120329869-A1 | BENZYLOXY ANILIDE DERIVATIVES USEFUL AS POTASSIUM CHANNEL MODULATORS | VALEANT PHARMACEUTICALS INTERNATIONAL | 2012-12-27 | — | — | US | disclosed |
| US-8188314-B2 | Benzyloxy anilide derivatives useful as potassium channel modulators | VALEANT PHARMACEUTICALS INTERNATIONAL (US) | 2012-05-29 | — | — | US | disclosed |
| US-20090326059-A1 | BENZYLOXY ANILIDE DERIVATIVES USEFUL AS POTASSIUM CHANNEL MODULATORS | VALEANT PHARMACEUTICALS INTERNATIONAL (US) | 2009-12-31 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120329869-A1 | BENZYLOXY ANILIDE DERIVATIVES USEFUL AS POTASSIUM CHANNEL MODULATORS | KCND2, KCNB2, KCNAB1 | MAOB 549/4885IDO1 2482/4885NR4A2 2275/4885 |
| US-20090326059-A1 | BENZYLOXY ANILIDE DERIVATIVES USEFUL AS POTASSIUM CHANNEL MODULATORS | KCND2, KCNB2, KCNAB1 | MAOB 549/4885IDO1 2482/4885NR4A2 2275/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.