SCHEMBL4330355

SCHEMBL4330355

C=CC(=O)NCCc1cc(C(C)(C)C)c(O)c(C(C)(C)C)c1

nearest known ligand 0.84

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
GAA P10253 7/20 0.84
KMT2A Q03164 5/20 0.55
MEN1 O00255 4/20 0.47
ALDH1A1 P00352 4/20 0.45
TSHR P16473 3/20 0.45
NPSR1 Q6W5P4 3/20 0.45
CYP1A2 P05177 2/20 0.45
CYP3A4 P08684 2/20 0.45
MAPK1 P28482 2/20 0.45
BLM P54132 2/20 0.45
ATM Q13315 2/20 0.45
HIF1A Q16665 2/20 0.45
USP2 O75604 1/20 0.45
CYP2D6 P10635 1/20 0.45
MAPT P10636 1/20 0.45
GSR P00390 2/20 0.44
LMNA P02545 3/20 0.41
RECQL P46063 1/20 0.41
TDP1 Q9NUW8 1/20 0.41
GMNN O75496 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4325063 0.85 GAA (0.70) GAAKMT2AMEN1ALDH1A1TSHR
SCHEMBL30708035 0.84 GAA (0.68) GAAKMT2AMEN1ALDH1A1TSHR
SCHEMBL9518040 0.83 GAA (0.61) GAAKMT2AMEN1ALDH1A1TSHR
SCHEMBL11581321 0.82 GAA (0.67) GAAKMT2AMEN1ALDH1A1TSHR
SCHEMBL4340637 0.80 GAA (0.56) GAAALDH1A1TSHRMAPK1BLM
SCHEMBL10363113 0.79 GAA (0.70) GAAKMT2AMEN1ALDH1A1TSHR
SCHEMBL11580932 0.79 GAA (0.62) GAAKMT2AMEN1ALDH1A1TSHR
SCHEMBL4569533 0.79 GAA (0.83) GAAKMT2AMEN1ALDH1A1GSR
SCHEMBL9517378 0.79 GAA (0.57) GAAKMT2AMEN1ALDH1A1GSR
SCHEMBL11703395 0.78 GAA (0.72) GAAKMT2AMEN1MAPTGSR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20090288855-A1 POSITIVE-TYPE RADIATION-SENSITIVE RESIN COMPOSITION FOR PRODUCING A METAL-PLATING FORMED MATERIAL, TRANSCRIPTION FILM AND PRODUCTION METHOD OF A METAL-PLATING FORMED MATERIAL JSR CORPORATION (JP) 2009-11-26 US disclosed
US-20070031758-A1 Positive-type radiation-sensitive resin composition for producing a metal-plating formed material, transcription film and production method of a metal-plating formed material JSR CORPORATION (JP) 2007-02-08 US disclosed
US-4281080-A TACKIFIERS FOR RUBBERS THE GOODYEAR TIRE & RUBBER COMPANY (US) 1981-07-28 US disclosed
US-4010140-A Age resistant resin compositions and admixtures useful as adhesives THE GOODYEAR TIRE & RUBBER COMPANY (US) 1977-03-01 US disclosed