Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 6/20 | 0.55 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.47 |
| ▸ | RAB9A | P51151 | 9/20 | 0.46 |
| ▸ | NPC1 | O15118 | 7/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.46 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.46 |
| ▸ | HTT | P42858 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.45 |
| ▸ | MEN1 | O00255 | 4/20 | 0.45 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.45 |
| ▸ | TP53 | P04637 | 3/20 | 0.45 |
| ▸ | TSHR | P16473 | 2/20 | 0.45 |
| ▸ | NFKB1 | P19838 | 2/20 | 0.45 |
| ▸ | NFKB2 | Q00653 | 2/20 | 0.45 |
| ▸ | RELA | Q04206 | 2/20 | 0.45 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.43 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.43 |
| ▸ | HPGD | P15428 | 1/20 | 0.43 |
| ▸ | RECQL | P46063 | 1/20 | 0.43 |
| ▸ | SORT1 | Q99523 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2941909 | 0.87 | SMN1; SMN2 (0.56) | SMN1; SMN2ALDH1A1RAB9ANPC1KDM4E | |
| SCHEMBL2944785 | 0.81 | SMN1; SMN2 (0.52) | SMN1; SMN2ALDH1A1RAB9ANPC1KDM4E | |
| SCHEMBL2949845 | 0.80 | SMN1; SMN2 (0.57) | SMN1; SMN2ALDH1A1RAB9ANPC1KDM4E | |
| SCHEMBL2948943 | 0.80 | SMN1; SMN2 (0.50) | SMN1; SMN2ALDH1A1RAB9ANPC1KDM4E | |
| SCHEMBL2945609 | 0.80 | SMN1; SMN2 (0.57) | SMN1; SMN2ALDH1A1RAB9ANPC1KDM4E | |
| SCHEMBL2949746 | 0.79 | SMN1; SMN2 (0.57) | SMN1; SMN2ALDH1A1RAB9ANPC1KDM4E | |
| SCHEMBL2946682 | 0.78 | SMN1; SMN2 (0.48) | SMN1; SMN2ALDH1A1RAB9ANPC1KDM4E | |
| SCHEMBL13291230 | 0.78 | SMN1; SMN2 (0.50) | SMN1; SMN2ALDH1A1RAB9ANPC1KDM4E | |
| SCHEMBL2947441 | 0.78 | SMN1; SMN2 (0.53) | SMN1; SMN2ALDH1A1RAB9ANPC1KDM4E | |
| SCHEMBL2945014 | 0.77 | SMN1; SMN2 (0.54) | SMN1; SMN2ALDH1A1RAB9ANPC1KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7605158-B2 | Carbamoyl-type benzofuran derivatives | MITSUBISHI TANABE PHARMA CORPORATION (JP) | 2009-10-20 | — | — | US | disclosed |
| CN-100430392-C | Carbamoyl-type benzofuran derivatives | TANABE SEIYAKU CO (JP) | 2008-11-05 | — | — | CN | disclosed |
| US-20060247273-A1 | Carbamoyl-type benzofuran derivatives | MITSUBISHI TANABE PHARMA CORPORATION (JP) | 2006-11-02 | — | — | US | disclosed |
| CN-1856488-A | Carbamoyl-type benzofuran derivatives | TANABE SEIYAKU CO (JP) | 2006-11-01 | — | — | CN | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20060247273-A1 | Carbamoyl-type benzofuran derivatives | F12, F2, F3 | SMN1; SMN2 4587/4885ALDH1A1 1153/4885RAB9A 2276/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.