Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | ESR1 | P03372 | 1/20 | 0.40 |
| ▸ | NR3C1 | P04150 | 1/20 | 0.40 |
| ▸ | PGR | P06401 | 1/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.40 |
| ▸ | SLC6A4 | P31645 | 11/20 | 0.38 |
| ▸ | SLC6A2 | P23975 | 5/20 | 0.38 |
| ▸ | SLC6A3 | Q01959 | 5/20 | 0.38 |
| ▸ | PDK2 | Q15119 | 2/20 | 0.36 |
| ▸ | HRH3 | Q9Y5N1 | 7/20 | 0.35 |
| ▸ | ACACB | O00763 | 1/20 | 0.33 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.33 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4316512 | 0.86 | SLC6A4 (0.52) | SLC6A4SLC6A2SLC6A3HRH3 | |
| SCHEMBL4327372 | 0.84 | SLC6A4 (0.41) | SLC6A4SLC6A2SLC6A3PDK2HRH3 | |
| SCHEMBL4323128 | 0.83 | SLC6A4 (0.55) | SLC6A4SLC6A2SLC6A3HRH3 | |
| SCHEMBL4316957 | 0.83 | SLC6A4 (0.39) | MAPTSLC6A4SLC6A2SLC6A3HRH3 | |
| SCHEMBL4451508 | 0.82 | SLC6A4 (0.46) | SLC6A4SLC6A2SLC6A3HRH3 | |
| SCHEMBL4338664 | 0.81 | SLC6A4 (0.48) | SLC6A4SLC6A2SLC6A3HRH3 | |
| SCHEMBL4326089 | 0.81 | SLC6A4 (0.45) | SLC6A4SLC6A2SLC6A3HRH3 | |
| SCHEMBL4321649 | 0.80 | SLC6A4 (0.47) | SLC6A4SLC6A2SLC6A3HRH3 | |
| SCHEMBL4325036 | 0.79 | SLC6A2 (0.50) | SLC6A4SLC6A2SLC6A3 | |
| SCHEMBL4468394 | 0.79 | SLC6A4 (0.41) | SLC6A4SLC6A2SLC6A3HRH3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009118765-A2 | NOVEL MONOAMINE RE-UPTAKE INHIBITOR | PANACEA BIOTEC LIMITED (GB) | 2009-10-01 | — | — | WO | disclosed |