Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4448622 | 0.89 | HRH3 (0.55) | HRH3KCNH2 | |
| SCHEMBL4325691 | 0.83 | HRH3 (0.58) | HRH3KCNH2 | |
| SCHEMBL4447050 | 0.81 | HRH3 (0.66) | HRH3KCNH2 | |
| SCHEMBL4322314 | 0.80 | HRH3 (0.85) | HRH3KCNH2 | |
| SCHEMBL4326935 | 0.79 | HRH3 (0.65) | HRH3KCNH2 | |
| SCHEMBL4320408 | 0.79 | HRH3 (0.72) | HRH3KCNH2 | |
| SCHEMBL4324934 | 0.78 | HRH3 (0.67) | HRH3KCNH2 | |
| SCHEMBL4314870 | 0.78 | HRH3 (0.71) | HRH3KCNH2 | |
| SCHEMBL4323744 | 0.78 | HRH3 (0.69) | HRH3KCNH2 | |
| SCHEMBL4328864 | 0.78 | HRH3 (0.69) | HRH3KCNH2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009143153-A1 | SUBSTITUTED PYRROLIDINE AMIDES AS MODULATORS OF THE HISTAMINE H3 RECEPTOR | JANSSEN PHARMACEUTICA NV (BE) | 2009-11-26 | — | — | WO | claimed |