Methoxychlor

Methoxychlor

SCHEMBL4331931

COc1ccc(C(c2ccc(OC)cc2)C(Cl)(Cl)Cl)cc1.COc1ccc(C(c2ccc(OC)cc2)C(Cl)(Cl)Cl)cc1

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAPK1 P28482 4/20 1.00
TDP1 Q9NUW8 4/20 1.00
TSHR P16473 2/20 1.00
L3MBTL1 Q9Y468 2/20 1.00
ALDH1A1 P00352 1/20 1.00
LMNA P02545 1/20 0.54
TP53 P04637 1/20 0.54
HPGD P15428 1/20 0.54
HIF1A Q16665 1/20 0.54
ESR2 Q92731 2/20 0.52
ESR1 P03372 1/20 0.52
CA1 P00915 2/20 0.50
CA2 P00918 2/20 0.50
CA7 P43166 2/20 0.50
CA9 Q16790 2/20 0.50
CA12 O43570 1/20 0.50
CA14 Q9ULX7 1/20 0.50
SLC2A1 P11166 1/20 0.44
CYP1A2 P05177 1/20 0.42
CYP2D6 P10635 1/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Methoxychlor SCHEMBL116390 1.00 MAPK1 (1.00) MAPK1TDP1TSHRL3MBTL1ALDH1A1
Methoxychlor SCHEMBL27511605 0.98 MAPK1 (0.96) MAPK1TDP1TSHRL3MBTL1ALDH1A1
Methoxychlor SCHEMBL27696157 0.98 TDP1 (0.96) MAPK1TDP1TSHRL3MBTL1ALDH1A1
Methoxychlor SCHEMBL27256466 0.98 MAPK1 (0.96) MAPK1TDP1TSHRL3MBTL1ALDH1A1
Methoxychlor SCHEMBL27568941 0.98 MAPK1 (0.96) MAPK1TDP1TSHRL3MBTL1ALDH1A1
Methoxychlor SCHEMBL28005408 0.98 MAPK1 (0.96) MAPK1TDP1TSHRL3MBTL1ALDH1A1
Methoxychlor SCHEMBL9539352 0.98 MAPK1 (0.96) MAPK1TDP1TSHRL3MBTL1ALDH1A1
Methoxychlor SCHEMBL27528278 0.98 MAPK1 (0.96) MAPK1TDP1TSHRL3MBTL1ALDH1A1
Methoxychlor SCHEMBL27937411 0.98 MAPK1 (0.96) MAPK1TDP1TSHRL3MBTL1ALDH1A1
Methoxychlor SCHEMBL27610102 0.98 MAPK1 (0.96) MAPK1TDP1TSHRL3MBTL1ALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-105658638-A compounds with insecticidal activity 拜耳作物科学股份公司 2016-06-08 CN disclosed
CN-101978892-B Bamboo vinegar anti-alcoholic beverage and preparation method thereof ZHIYONG WANG 2012-08-15 CN disclosed
CN-101972025-B Bamboo vinegar health care beverage and preparation method thereof ZHIYONG WANG 2012-07-25 CN disclosed
CN-102105061-A Device and method for controlling insects WYETH CORP 2011-06-22 CN disclosed
CN-201859340-U Monitoring system for extracting and purifying bamboo vinegar ZHIYONG WANG 2011-06-08 CN disclosed
CN-101978892-A Bamboo vinegar anti-alcoholic beverage and preparation method thereof ZHIYONG WANG 2011-02-23 CN disclosed
CN-101972025-A Bamboo vinegar health care beverage and preparation method thereof ZHIYONG WANG 2011-02-16 CN disclosed
US-20090318393-A1 Film-forming liquid formulations for controlled release of pesticides POLY-MED, INC. 2009-12-24 US disclosed
US-4767773-A BENZOYL UREAS AND BENZOFURANYL CARBAMATE COMPONENTS RHONE-POULENC NEDERLAND B.V. (NL) 1988-08-30 US disclosed
EP-0237960-A2 Thickening aqueous systems BASF Corporation (US) 1987-09-23 EP disclosed