Known targets — ChEMBL curated mechanism
The experimentally established mechanism targets of Bicarbonate. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Bicarbonate SCHEMBL10899209 | 0.93 | CA1 (0.83) | — | |
| Bicarbonate SCHEMBL8353590 | 0.93 | CA1 (0.83) | — | |
| Bicarbonate SCHEMBL180351 | 0.93 | CA1 (0.83) | — | |
| Bicarbonate SCHEMBL14696469 | 0.93 | CA1 (0.83) | — | |
| Bicarbonate SCHEMBL11132176 | 0.93 | CA1 (0.83) | — | |
| Bicarbonate SCHEMBL3848193 | 0.93 | CA1 (0.83) | — | |
| Bicarbonate SCHEMBL7073013 | 0.93 | CA1 (0.83) | — | |
| Bicarbonate SCHEMBL21057509 | 0.93 | CA1 (0.83) | — | |
| Bicarbonate SCHEMBL21327769 | 0.93 | CA1 (0.83) | — | |
| Bicarbonate SCHEMBL1460175 | 0.93 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116745283-A | Heterocyclic derivatives for the treatment of TRPM3 mediated disorders | 勒芬天主教大学 | 2023-09-12 | — | — | CN | disclosed |
| US-7625463-B2 | Methods for the preparation of fibrous superabsorbent composite containing cellulose | WEYERHAEUSER NR COMPANY (US) | 2009-12-01 | — | — | US | disclosed |
| US-20080078515-A1 | Methods for the preparation of fibrous superabsorbent composite containing cellulose | WEYERHAEUSER CO. (US) | 2008-04-03 | — | — | US | disclosed |
| US-20080081165-A1 | Fibrous superabsorbent composite containing cellulose | WEYERHAEUSER CO. (US) | 2008-04-03 | — | — | US | disclosed |