⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL779258 | 0.83 | LPAR3 (0.37) | — | |
| SCHEMBL1559671 | 0.80 | LPAR2 (0.35) | — | |
| SCHEMBL28985810 | 0.79 | CYP3A4 (0.48) | — | |
| SCHEMBL436759 | 0.79 | LPAR2 (0.36) | — | |
| SCHEMBL776819 | 0.78 | LPAR3 (0.55) | — | |
| SCHEMBL23037249 | 0.77 | — | — | |
| SCHEMBL26661425 | 0.77 | — | — | |
| SCHEMBL28868290 | 0.77 | LPAR3 (0.58) | — | |
| Phosphine SCHEMBL27341952 | 0.77 | LPAR3 (0.53) | — | |
| SCHEMBL209829 | 0.76 | TSHR (0.52) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 38 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-102341402-A | Thienopyridines as pharmacologically active agents | COUNCIL SCIENT IND RES | 2012-02-01 | — | — | CN | claimed |
| US-5091491-A | Water-soluble allylphosphonate copolymers | W. R. GRACE & CO.-CONN. (US) | 1992-02-25 | — | — | US | claimed |
| US-20260146050-A1 | KRAS DEGRADING COMPOUNDS COMPRISING SPIROCYCLIC ANNULATED 2 AMINO-3-CYANO THIOPHENES | BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) | 2026-05-28 | — | — | US | disclosed |
| CN-121005716-A | 2-Amino-3-cyano thiophene derivative, preparation method and application thereof | 苏州朗睿生物医药有限公司 | 2025-11-25 | — | — | CN | disclosed |
| WO-2025059366-A1 | RAS INHIBITORS | KUMQUAT BIOSCIENCES INC. (US) | 2025-03-20 | — | — | WO | disclosed |
| CN-107857778-B | Process for preparing α -aminonitriles containing phosphono groups | 江苏乐斯化学有限公司 | 2020-03-24 | — | — | CN | disclosed |
| CN-103880881-A | Method for preparing allyl phosphonic acid dimethyl ester | XIANGCHENG RES INST OF SUZHOU UNIVERSITY OF SCIENCE AND TECHNOLOGY | 2014-06-25 | — | — | CN | disclosed |
| CN-103880881-A | Method for preparing allyl phosphonic acid dimethyl ester | XIANGCHENG RES INST OF SUZHOU UNIVERSITY OF SCIENCE AND TECHNOLOGY | 2014-06-25 | — | — | CN | disclosed |
| EP-1489158-B1 | Friction modifier composition | SANYO CHEMICAL IND LTD (JP) | 2012-06-20 | — | — | EP | disclosed |
| CN-102341402-A | Thienopyridines as pharmacologically active agents | COUNCIL SCIENT IND RES | 2012-02-01 | — | — | CN | disclosed |
| CN-102245614-A | Methylene amines of thieno [2, 3-d] pyrimidine and their use as adenosine A2a receptor antagonists | JANSSEN PHARMACEUTICA NV | 2011-11-16 | — | — | CN | disclosed |
| CN-1295586-A | Coloured polyurethanes | AVECIA LTD (GB) | 2001-05-16 | — | — | CN | disclosed |
| US-5124047-A | Allylphosphonate copolymer, in aqueous systems | W. R. GRACE & CO.-CONN. (US) | 1992-06-23 | — | — | US | disclosed |
| US-5091491-A | Water-soluble allylphosphonate copolymers | W. R. GRACE & CO.-CONN. (US) | 1992-02-25 | — | — | US | disclosed |
| US-4377537-A | FROM TRIARYL PHOSPHITE AND ALKYL PHOSPHITE OR PHOSPHONOUS ACID DIARYL ESTER AND PHOSPHONOUS ACID DIALKYL ESTER | BAYER AKTIENGESELLSCHAFT (DE) | 1983-03-22 | — | — | US | disclosed |
| US-4257987-A | SYNERGISTIC ARTHROPODICIDES | BAYER AKTIENGESELLSCHAFT (DE) | 1981-03-24 | — | — | US | disclosed |
| US-4257942-A | New water-insoluble azo dyes | AZIENDE COLORI NAZIONALI AFFINI ACNA S.P.A. (IT) | 1981-03-24 | — | — | US | disclosed |
| US-4048374-A | Functional organophosphonic acid esters as preservative adhesion promoting agents and coating for metals | DYNAMIT NOBEL AKTIENGESELLSCHAFT (DT) | 1977-09-13 | — | — | US | disclosed |
| US-4029679-A | PROTECTIVE METAL COATING | DYNAMIT NOBEL AKTIENGESELLSCHAFT (DT) | 1977-06-14 | — | — | US | disclosed |
| US-4017564-A | NICKEL OR COBALT CATALYST | BAYER AKTIENGESELLSCHAFT (DT) | 1977-04-12 | — | — | US | disclosed |