Known targets — ChEMBL curated mechanism
The experimentally established mechanism targets of Lithium Ion. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 1/20 | 0.67 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.67 |
| ▸ | CA5A | P35218 | 1/20 | 0.46 |
| ▸ | CA5B | Q9Y2D0 | 1/20 | 0.46 |
| ▸ | TSHR | P16473 | 3/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.36 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Water SCHEMBL17500219 | 0.94 | MEN1 (0.60) | MEN1KMT2ACA5ACA5BTSHR | |
| Water SCHEMBL7041052 | 0.94 | MEN1 (0.60) | MEN1KMT2ACA5ACA5BTSHR | |
| Water SCHEMBL28699228 | 0.94 | MEN1 (0.60) | MEN1KMT2ACA5ACA5BTSHR | |
| SCHEMBL48481 | 0.94 | — | — | |
| Lithium Ion SCHEMBL26914837 | 0.94 | MEN1 (0.75) | MEN1KMT2ACA5ACA5BTSHR | |
| Lithium Ion SCHEMBL22864 | 0.94 | — | — | |
| SCHEMBL4822864 | 0.94 | MEN1 (0.75) | MEN1KMT2ACA5ACA5BTSHR | |
| SCHEMBL5675024 | 0.94 | MEN1 (0.75) | MEN1KMT2ACA5ACA5BTSHR | |
| SCHEMBL23273248 | 0.88 | MEN1 (0.67) | MEN1KMT2ACA5ACA5BTSHR | |
| Hydrochloric Acid SCHEMBL23243661 | 0.88 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 20 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8727825-B2 | Life jacket | TSOLKAS ALEXANDER (DE) | 2014-05-20 | — | — | US | disclosed |
| US-20120244766-A1 | LIFE JACKET | TSOLKAS ALEXANDER (DE) | 2012-09-27 | — | — | US | disclosed |
| US-7510324-B2 | Method of inspecting articles using imaging inspection apparatus with directional cooling | ENDICOTT INTERCONNECT TECHNOLOGIES, INC. (US) | 2009-03-31 | — | — | US | disclosed |
| US-7490984-B2 | Method of making an imaging inspection apparatus with improved cooling | ENDICOTT INTERCONNECT TECHNOLOGIES, INC. (US) | 2009-02-17 | — | — | US | disclosed |
| US-20080170670-A1 | Method of inspecting articles using imaging inspection apparatus with directional cooling | ENDICOTT INTERCONNECT TECHNOLOGIES , INC. (US) | 2008-07-17 | — | — | US | disclosed |
| US-20080144768-A1 | Method of making an imaging inspection apparatus with improved cooling | ENDICOTT INTERCONNECT TECHNOLOGIES, INC. (US) | 2008-06-19 | — | — | US | disclosed |
| US-7354197-B2 | Imaging inspection apparatus with improved cooling | ENDICOTT INTERCONNECT TECHNOLOGIES, INC. (US) | 2008-04-08 | — | — | US | disclosed |
| US-7261466-B2 | Imaging inspection apparatus with directional cooling | ENDICOTT INTERCONNECT TECHNOLOGIES, INC. (US) | 2007-08-28 | — | — | US | disclosed |
| EP-1508552-B1 | Woodwool chips based construction product | HERAKLITH AG (AT) | 2007-05-16 | — | — | EP | disclosed |
| US-20070009084-A1 | Imaging inspection apparatus with directional cooling | ENDICOTT INTERCONNECT TECHNOLOGIES, INC. (US) | 2007-01-11 | — | — | US | disclosed |
| US-20060274891-A1 | Imaging inspection apparatus with improved cooling | ENDICOTT INTERCONNECT TECHNOLOGIES, INC. (US) | 2006-12-07 | — | — | US | disclosed |
| EP-1508552-A2 | Woodwool chips based construction product | HERAKLITH AG (AT) | 2005-02-23 | — | — | EP | disclosed |
| US-6784356-B1 | ADDING A TETRABORATE SALT TO MINIMIZE ACID FORMATION AND PRESSURE BUILDUP WITHIN THE PHASE CHANGE MATERIAL WHEN SEALED IN A CONTAINER | MODINE MANUFACTURING COMPANY | 2004-08-31 | — | — | US | disclosed |
| US-6619841-B2 | Fluid-cooled x-ray tube | SIEMENS AKTIENGESELLSCHAFT (DE) | 2003-09-16 | — | — | US | disclosed |
| EP-1043381-B1 | Phase change material with inhibitor and a method of making the same | MODINE MFG CO (US) | 2003-06-18 | — | — | EP | disclosed |
| EP-0962513-B1 | Density stabilized phase change material | MODINE MFG CO (US) | 2003-04-16 | — | — | EP | disclosed |
| US-20020163995-A1 | Fluid-cooled x-ray tube | SIEMENS AKTIENGESELLSCHAFT (DE) | 2002-11-07 | — | — | US | disclosed |
| EP-1043381-A1 | Phase change material with inhibitor and a method of making the same | MODINE MANUFACTURING COMPANY (US) | 2000-10-11 | — | — | EP | disclosed |
| US-6083418-A | MIXTURE OF GROUP 1A, GROUP 2A NITRATE HYDRATES | MODINE MANUFACTURING COMPANY (US) | 2000-07-04 | — | — | US | disclosed |
| EP-0962513-A1 | Density stabilized phase change material | MODINE MANUFACTURING COMPANY (US) | 1999-12-08 | — | — | EP | disclosed |