Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ELANE | P08246 | 1/20 | 0.48 |
| ▸ | MAPT | P10636 | 3/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.46 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.46 |
| ▸ | GAA | P10253 | 1/20 | 0.46 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.41 |
| ▸ | ATM | Q13315 | 2/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.41 |
| ▸ | LMNA | P02545 | 2/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.40 |
| ▸ | HPGD | P15428 | 2/20 | 0.40 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | ESR1 | P03372 | 1/20 | 0.40 |
| ▸ | ITGB3 | P05106 | 1/20 | 0.40 |
| ▸ | ITGA2B | P08514 | 1/20 | 0.40 |
| ▸ | HMGB1 | P09429 | 1/20 | 0.40 |
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
| ▸ | GGT1 | P19440 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Acetic Acid SCHEMBL27442529 | 0.90 | ELANE (0.48) | ELANEMAPTALDH1A1HSP90AA1GAA | |
| Methyl Alcohol SCHEMBL28471241 | 0.87 | TDP1 (0.47) | ELANEMAPTALDH1A1HSP90AA1GAA | |
| Benzene SCHEMBL7925278 | 0.87 | TDP1 (0.50) | ELANEMAPTALDH1A1TDP1ATM | |
| SCHEMBL3302 | 0.87 | TDP1 (0.50) | ELANEMAPTALDH1A1TDP1ATM | |
| SCHEMBL370622 | 0.87 | TDP1 (0.50) | ELANEMAPTALDH1A1TDP1ATM | |
| Pyruvate SCHEMBL27959193 | 0.86 | ELANE (0.46) | ELANEMAPTALDH1A1HSP90AA1GAA | |
| Hydrochloric Acid SCHEMBL3896561 | 0.85 | TDP1 (0.48) | ELANEMAPTALDH1A1TDP1ATM | |
| SCHEMBL10975650 | 0.85 | TDP1 (0.48) | ELANEMAPTALDH1A1TDP1ATM | |
| Bicarbonate SCHEMBL29032037 | 0.85 | TDP1 (0.48) | ELANEMAPTALDH1A1TDP1ATM | |
| SCHEMBL11224568 | 0.85 | TDP1 (0.48) | ELANEMAPTALDH1A1TDP1ATM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2032142-A2 | NOVEL COMPOUNDS | GLAXO GROUP LIMITED (GB) | 2009-03-11 | — | — | EP | disclosed |
| WO-2007147109-A2 | NOVEL COMPOUNDS | GLAXO GROUP LIMITED (GB) | 2007-12-21 | — | — | WO | disclosed |