Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 2/20 | 0.52 |
| ▸ | KMT2A | Q03164 | 6/20 | 0.45 |
| ▸ | MEN1 | O00255 | 4/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.45 |
| ▸ | USP2 | O75604 | 1/20 | 0.45 |
| ▸ | LMNA | P02545 | 1/20 | 0.45 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.44 |
| ▸ | NPC1 | O15118 | 1/20 | 0.43 |
| ▸ | RAB9A | P51151 | 1/20 | 0.43 |
| ▸ | NOX1 | Q9Y5S8 | 1/20 | 0.43 |
| ▸ | GAA | P10253 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 1/20 | 0.43 |
| ▸ | HTT | P42858 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
| ▸ | CNR2 | P34972 | 1/20 | 0.43 |
| ▸ | GLA | P06280 | 2/20 | 0.42 |
| ▸ | NR1H2 | P55055 | 1/20 | 0.42 |
| ▸ | NR1H3 | Q13133 | 1/20 | 0.42 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.41 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7324210 | 0.94 | TSHR (0.50) | TSHRKMT2AMEN1ALDH1A1USP2 | |
| SCHEMBL10652285 | 0.92 | TSHR (0.48) | TSHRKMT2AMEN1ALDH1A1USP2 | |
| SCHEMBL10650204 | 0.92 | TSHR (0.48) | TSHRKMT2AMEN1ALDH1A1USP2 | |
| SCHEMBL133939 | 0.88 | TSHR (0.55) | TSHRKMT2AMEN1ALDH1A1TAAR1 | |
| SCHEMBL11142653 | 0.87 | TSHR (0.59) | TSHRKMT2AMEN1ALDH1A1USP2 | |
| SCHEMBL1408147 | 0.87 | MEN1 (0.42) | TSHRKMT2AMEN1ALDH1A1GAA | |
| SCHEMBL10453658 | 0.87 | TSHR (0.59) | TSHRKMT2AMEN1ALDH1A1USP2 | |
| Hydrochloric Acid SCHEMBL11299552 | 0.86 | TSHR (0.53) | TSHRKMT2AMEN1ALDH1A1TAAR1 | |
| SCHEMBL9176797 | 0.85 | TSHR (0.57) | TSHRKMT2AMEN1ALDH1A1USP2 | |
| Hydrochloric Acid SCHEMBL10705984 | 0.84 | TSHR (0.52) | TSHRKMT2AMEN1ALDH1A1TAAR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009102707-A2 | SUBSTITUTED OXAZAPHOSPHORINES | AUSPEX PHARMACEUTICALS, INC. (US) | 2009-08-20 | — | — | WO | disclosed |
| EP-0289262-A2 | Omega-quaternary ammonium alkyl esters and thioesters of acidic nonsteroidal antiinflammatory drugs | SYNTEX PHARMACEUTICALS INTERNATIONAL LIMITED (BM) | 1988-11-02 | — | — | EP | disclosed |