Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 3/20 | 0.46 |
| ▸ | RECQL | P46063 | 2/20 | 0.46 |
| ▸ | GLA | P06280 | 1/20 | 0.46 |
| ▸ | HPGD | P15428 | 1/20 | 0.46 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.46 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.46 |
| ▸ | BLM | P54132 | 1/20 | 0.46 |
| ▸ | CES2 | O00748 | 4/20 | 0.41 |
| ▸ | CES1 | P23141 | 4/20 | 0.41 |
| ▸ | HAO1 | Q9UJM8 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 2/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.41 |
| ▸ | ENPP2 | Q13822 | 2/20 | 0.38 |
| ▸ | SLC25A20 | O43772 | 3/20 | 0.38 |
| ▸ | TP53 | P04637 | 2/20 | 0.38 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.38 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL432423 | 1.00 | TSHR (0.46) | TSHRRECQLGLAHPGDMAPK1 | |
| SCHEMBL432073 | 1.00 | TSHR (0.46) | TSHRRECQLGLAHPGDMAPK1 | |
| SCHEMBL28866657 | 0.90 | TSHR (0.56) | TSHRRECQLGLAHPGDMAPK1 | |
| SCHEMBL28866655 | 0.90 | TSHR (0.56) | TSHRRECQLGLAHPGDMAPK1 | |
| SCHEMBL29396249 | 0.90 | TSHR (0.56) | TSHRRECQLGLAHPGDMAPK1 | |
| SCHEMBL6117756 | 0.76 | KMT2A (0.48) | TSHRCES2CES1HAO1MAPT | |
| SCHEMBL28922059 | 0.76 | KMT2A (0.48) | TSHRCES2CES1HAO1MAPT | |
| SCHEMBL29399044 | 0.76 | RECQL (0.70) | TSHRRECQLGLAHPGDMAPK1 | |
| SCHEMBL29398892 | 0.76 | RECQL (0.76) | TSHRRECQLGLAHPGDMAPK1 | |
| SCHEMBL29398542 | 0.76 | RECQL (0.76) | TSHRRECQLGLAHPGDMAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2596050-B1 | EMULSIONS OF AMINOFUNCTIONAL SILICONES | DOW SILICONES CORP (US) | 2018-11-14 | — | — | EP | disclosed |
| EP-3004219-B1 | PROCESS FOR PREPARING AMINOFUNCTIONAL SILICONE EMULSIONS | DOW CORNING (US) | 2018-04-04 | — | — | EP | disclosed |
| EP-3004219-A1 | PROCESS FOR PREPARING AMINOFUNCTIONAL SILICONE EMULSIONS | Dow Corning Corporation (US) | 2016-04-13 | — | — | EP | disclosed |
| US-20160038403-A1 | Process For Preparing Aminofunctional Silicone Emulsions | DOW COMING CORPORATION (US) | 2016-02-11 | — | — | US | disclosed |
| US-9017650-B2 | Emulsions of aminofunctional silicones | DOW CORNING CORPORATION (US) | 2015-04-28 | — | — | US | disclosed |
| WO-2014193636-A1 | PROCESS FOR PREPARING AMINOFUNCTIONAL SILICONE EMULSIONS | DOW CORNING CORPORATION (US) | 2014-12-04 | — | — | WO | disclosed |
| EP-2596050-A1 | EMULSIONS OF AMINOFUNCTIONAL SILICONES | Dow Corning Corporation (US) | 2013-05-29 | — | — | EP | disclosed |
| US-20130121949-A1 | Emulsions Of Aminofunctional Silicones | DOW CORNING CORPORATION (US) | 2013-05-16 | — | — | US | disclosed |
| WO-2012012524-A1 | EMULSIONS OF AMINOFUNCTIONAL SILICONES | DOW CORNING CORPORATION (US) | 2012-01-26 | — | — | WO | disclosed |