Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGD | P15428 | 1/20 | 0.52 |
| ▸ | MEN1 | O00255 | 2/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.51 |
| ▸ | MAPT | P10636 | 1/20 | 0.51 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.47 |
| ▸ | USP2 | O75604 | 1/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.45 |
| ▸ | PRMT5 | O14744 | 1/20 | 0.44 |
| ▸ | WDR77 | Q9BQA1 | 1/20 | 0.44 |
| ▸ | RECQL | P46063 | 1/20 | 0.43 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.43 |
| ▸ | PREP | P48147 | 1/20 | 0.42 |
| ▸ | USP30 | Q70CQ3 | 1/20 | 0.41 |
| ▸ | GPR119 | Q8TDV5 | 2/20 | 0.41 |
| ▸ | CHEK2 | O96017 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29244745 | 1.00 | HPGD (0.52) | HPGDMEN1KMT2AALDH1A1MAPT | |
| SCHEMBL13219346 | 0.91 | HPGD (0.51) | HPGDMEN1KMT2AALDH1A1MAPT | |
| SCHEMBL17392565 | 0.91 | HPGD (0.51) | HPGDMEN1KMT2AALDH1A1MAPT | |
| SCHEMBL65675 | 0.91 | HPGD (0.51) | HPGDMEN1KMT2AALDH1A1MAPT | |
| SCHEMBL214960 | 0.88 | HPGD (0.50) | HPGDMEN1KMT2AALDH1A1MAPT | |
| SCHEMBL24611623 | 0.88 | HPGD (0.52) | HPGDMEN1KMT2AALDH1A1MAPT | |
| SCHEMBL3955730 | 0.88 | HPGD (0.52) | HPGDMEN1KMT2AALDH1A1MAPT | |
| SCHEMBL6498939 | 0.87 | HPGD (0.51) | HPGDMEN1KMT2AALDH1A1MAPT | |
| SCHEMBL22388002 | 0.87 | HPGD (0.51) | HPGDMEN1KMT2AALDH1A1MAPT | |
| SCHEMBL21993750 | 0.87 | HPGD (0.51) | HPGDMEN1KMT2AALDH1A1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024206628-A1 | MODULATORS OF MYC FAMILY PROTO-ONCOGENE PROTEIN | NALO THERAPEUTICS (US) | 2024-10-03 | — | — | WO | disclosed |
| CN-104662001-A | METHOD FOR PRODUCING cis-5-HYDROXY-2-PIPERIDINECARBOXYLIC ACID DERIVATIVE, AND METHOD FOR PURIFYING cis-5-HYDROXY-2-PIPERIDINECARBOXYLIC ACID | API CORP | 2015-05-27 | — | — | CN | disclosed |
| WO-2009132202-A2 | MACROCYCLIC COMPOUNDS AND THEIR USE AS KINASE INHIBITORS | INCYTE CORPORATION (US) | 2009-10-29 | — | — | WO | disclosed |
| CN-101405265-A | Amido compounds and their use as pharmaceuticals | INCYTE CORP (US) | 2009-04-08 | — | — | CN | disclosed |