SCHEMBL4334282

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL4334510	0.86	MAPK1 (0.39)	SCN9AMAPK1MAPK3LIMK1CSNK1D
	SCHEMBL4343384	0.85	MAPK1 (0.39)	MAPK1MAPK3ALPLPIN1
	SCHEMBL4343383	0.84	MAPK1 (0.41)	SCN9AMAPK1MAPK3ALPLPIN1
	SCHEMBL4327408	0.83	HDAC4 (0.42)	MAPK1MAPK3ALPLAKR1C3AKR1C2
	SCHEMBL4333011	0.81	MAPK1 (0.51)	MAPK1MAPK3CDK2GSK3AGSK3B
	SCHEMBL2861275	0.80	CA12 (0.50)	MAPK1ALPLAKR1C3AKR1C2DHODH
	SCHEMBL4335969	0.79	MAPK1 (0.37)	MAPK1MAPK3ALPLPIN1
	SCHEMBL2870995	0.79	MCHR1 (0.47)	KDR
	SCHEMBL4334329	0.78	NPC1 (0.41)	MAPK1MAPK3ALPLDHODHCSNK1D
	SCHEMBL6425955	0.77	TP53 (0.39)	SCN9AHPGDSALPLPTGER3LIMK1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.