Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EPHX1 | P07099 | 2/20 | 0.45 |
| ▸ | CYP19A1 | P11511 | 2/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.38 |
| ▸ | NPSR1 | Q6W5P4 | 4/20 | 0.38 |
| ▸ | MAPT | P10636 | 3/20 | 0.38 |
| ▸ | TSHR | P16473 | 2/20 | 0.38 |
| ▸ | LMNA | P02545 | 2/20 | 0.38 |
| ▸ | USP2 | O75604 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 3/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.37 |
| ▸ | MAPK1 | P28482 | 4/20 | 0.36 |
| ▸ | HPGD | P15428 | 2/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
| ▸ | MITF | O75030 | 2/20 | 0.36 |
| ▸ | HTT | P42858 | 2/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.36 |
| ▸ | NPC1 | O15118 | 1/20 | 0.36 |
| ▸ | TP53 | P04637 | 1/20 | 0.36 |
| ▸ | RAB9A | P51151 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL498159 | 0.89 | EPHX1 (0.42) | EPHX1CYP19A1ALDH1A1NPSR1MAPT | |
| SCHEMBL4331089 | 0.83 | CYP19A1 (0.46) | EPHX1CYP19A1ALDH1A1NPSR1MAPT | |
| SCHEMBL4343190 | 0.81 | EPHX1 (0.46) | EPHX1CYP19A1ALDH1A1NPSR1MAPT | |
| SCHEMBL3147326 | 0.81 | EPHX1 (0.46) | EPHX1CYP19A1ALDH1A1NPSR1MAPT | |
| SCHEMBL498355 | 0.81 | CYP19A1 (0.42) | EPHX1CYP19A1ALDH1A1NPSR1MAPT | |
| SCHEMBL498665 | 0.75 | EPHX1 (0.43) | EPHX1CYP19A1ALDH1A1NPSR1MAPT | |
| SCHEMBL498183 | 0.75 | EPHX1 (0.43) | EPHX1CYP19A1ALDH1A1NPSR1MAPT | |
| SCHEMBL5010580 | 0.72 | CYP19A1 (0.61) | EPHX1CYP19A1ALDH1A1NPSR1MAPT | |
| SCHEMBL21331615 | 0.71 | TDP1 (0.46) | EPHX1CYP19A1ALDH1A1NPSR1MAPT | |
| SCHEMBL19020458 | 0.71 | TDP1 (0.46) | EPHX1CYP19A1ALDH1A1NPSR1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2058300-B1 | SUCCINIC ACID DIESTER DERIVATIVE, PROCESS FOR PRODUCTION THEREOF, AND USE OF THE DERIVATIVE IN THE PRODUCTION OF PHARMACEUTICAL PREPARATION | DAINIPPON SUMITOMO PHARMA CO (JP) | 2013-01-09 | — | — | EP | disclosed |
| EP-2058300-A1 | SUCCINIC ACID DIESTER DERIVATIVE, PROCESS FOR PRODUCTION THEREOF, AND USE OF THE DERIVATIVE IN THE PRODUCTION OF PHARMACEUTICAL PREPARATION | Dainippon Sumitomo Pharma Co., Ltd. (JP) | 2009-05-13 | — | — | EP | disclosed |