SCHEMBL4335068

SCHEMBL4335068

CCCCCCCCc1ccc(-c2ccc(OCCCCCCCCOC(=O)c3cc(O)ccc3O)cc2)cc1

nearest known ligand 0.48

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
EGFR P00533 1/20 0.48
CA12 O43570 1/20 0.48
CA1 P00915 1/20 0.48
CA2 P00918 1/20 0.48
CA7 P43166 1/20 0.48
CA9 Q16790 1/20 0.48
CA14 Q9ULX7 1/20 0.48
NR5A1 Q13285 1/20 0.48
POLB P06746 1/20 0.47
RARB P10826 3/20 0.47
KAT8 Q9H7Z6 2/20 0.47
MEN1 O00255 1/20 0.46
USP2 O75604 1/20 0.46
ALDH1A1 P00352 1/20 0.46
LMNA P02545 1/20 0.46
CYP3A4 P08684 1/20 0.46
MAPK1 P28482 1/20 0.46
CASP1 P29466 1/20 0.46
KMT2A Q03164 1/20 0.46
SMN1; SMN2 Q16637 1/20 0.46

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29290466 0.84 CA12 (0.55) EGFRCA12CA1CA2CA7
SCHEMBL31125334 0.84 CA12 (0.67) CA12CA1CA2CA7CA9
SCHEMBL31125342 0.84 CA12 (0.67) CA12CA1CA2CA7CA9
SCHEMBL31125339 0.84 CA12 (0.67) CA12CA1CA2CA7CA9
SCHEMBL17107306 0.84 CA12 (0.67) CA12CA1CA2CA7CA9
SCHEMBL13422476 0.84 CA12 (0.67) CA12CA1CA2CA7CA9
SCHEMBL10581365 0.84 CA12 (0.67) CA12CA1CA2CA7CA9
SCHEMBL31125325 0.84 CA12 (0.67) CA12CA1CA2CA7CA9
SCHEMBL31125331 0.84 CA12 (0.67) CA12CA1CA2CA7CA9
SCHEMBL495935 0.84 CA12 (0.67) CA12CA1CA2CA7CA9

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1169293-B1 LIQUID CRYSTAL COMPOUNDS ROLIC AG (CH) 2009-07-22 EP disclosed
EP-1169293-B1 LIQUID CRYSTAL COMPOUNDS ROLIC AG (CH) 2009-07-22 EP disclosed
US-6733690-B1 ACRYLIC ESTER POLYMERS ROLIC AG (CH) 2004-05-11 US disclosed
EP-1169293-A1 LIQUID CRYSTAL COMPOUNDS Rolic AG (CH) 2002-01-09 EP disclosed
WO-2000055110-A1 LIQUID CRYSTAL COMPOUNDS ROLIC AG (CH) 2000-09-21 WO disclosed