Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | F2R | P25116 | 10/20 | 0.54 |
| ▸ | MAOB | P27338 | 5/20 | 0.45 |
| ▸ | MAOA | P21397 | 3/20 | 0.44 |
| ▸ | BCHE | P06276 | 2/20 | 0.44 |
| ▸ | ACHE | P22303 | 2/20 | 0.44 |
| ▸ | HDAC6 | Q9UBN7 | 2/20 | 0.37 |
| ▸ | PPARG | P37231 | 1/20 | 0.36 |
| ▸ | PPARD | Q03181 | 1/20 | 0.36 |
| ▸ | PPARA | Q07869 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4335517 | 0.87 | F2R (0.43) | F2RMAOBMAOABCHEACHE | |
| SCHEMBL14346247 | 0.83 | F2R (0.48) | F2RMAOBMAOABCHEACHE | |
| SCHEMBL14346228 | 0.79 | F2R (0.63) | F2RMAOBMAOABCHEACHE | |
| Hydrochloric Acid SCHEMBL4344473 | 0.78 | F2R (0.62) | F2RMAOBMAOABCHEACHE | |
| Trifluoroacetic Acid SCHEMBL4336033 | 0.74 | F2R (0.55) | F2RMAOBMAOABCHEACHE | |
| Trifluoroacetic Acid SCHEMBL4349250 | 0.74 | F2R (0.62) | F2RMAOBMAOABCHEACHE | |
| Trifluoroacetic Acid SCHEMBL4340439 | 0.74 | F2R (0.62) | F2RMAOBMAOABCHEACHE | |
| Trifluoroacetic Acid SCHEMBL6750517 | 0.74 | F2R (0.83) | F2RMAOBMAOABCHEACHE | |
| Trifluoroacetic Acid SCHEMBL4338976 | 0.72 | F2R (0.60) | F2RMAOBMAOABCHEACHE | |
| Trifluoroacetic Acid SCHEMBL6748422 | 0.72 | F2R (0.80) | F2R |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1391456-B1 | 2-IMINOIMIDAZOLE DERIVATIVES | EISAI R&D MAN CO LTD (JP) | 2009-07-22 | — | — | EP | disclosed |
| US-7304083-B2 | 2-iminoimidazole derivatives (2) | EISAI R&D MANAGEMENT CO., LTD. (JP) | 2007-12-04 | — | — | US | disclosed |
| US-20050004197-A1 | 2-iminoimidazole derivatives (2) | EISAI R&D MANAGEMENT CO., LTD. (JP) | 2005-01-06 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050004197-A1 | 2-iminoimidazole derivatives (2) | H1-2, H1-3, H1-4 | F2R 2393/4885MAOB 2255/4885MAOA 2680/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.