Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MIF | P14174 | 7/20 | 0.46 |
| ▸ | CD74 | P04233 | 3/20 | 0.44 |
| ▸ | TP53 | P04637 | 3/20 | 0.36 |
| ▸ | MAPT | P10636 | 3/20 | 0.36 |
| ▸ | POLB | P06746 | 2/20 | 0.36 |
| ▸ | ABHD6 | Q9BV23 | 1/20 | 0.36 |
| ▸ | RAB9A | P51151 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.35 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.35 |
| ▸ | PKM | P14618 | 1/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL433211 | 0.79 | MIF (0.46) | MIFCD74TP53MAPTPOLB | |
| SCHEMBL433212 | 0.79 | MIF (0.46) | MIFCD74TP53MAPTPOLB | |
| SCHEMBL435180 | 0.75 | MIF (0.43) | MIFCD74TP53MAPTPOLB | |
| SCHEMBL435181 | 0.75 | MIF (0.43) | MIFCD74TP53MAPTPOLB | |
| SCHEMBL10083366 | 0.74 | MAPT (0.41) | MIFCD74TP53MAPTPOLB | |
| SCHEMBL15380476 | 0.71 | MIF (0.44) | MIFCD74TP53MAPTPOLB | |
| SCHEMBL16412546 | 0.70 | MIF (0.44) | MIFCD74TP53MAPTPOLB | |
| SCHEMBL16413040 | 0.70 | MIF (0.44) | MIFCD74TP53MAPTPOLB | |
| SCHEMBL16421403 | 0.70 | MIF (0.57) | MIFCD74TP53MAPTPOLB | |
| SCHEMBL16419129 | 0.70 | MIF (0.57) | MIFCD74TP53MAPTPOLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012012410-A2 | KAPPA OPIOID RECEPTOR AGONISTS | DR. REDDY'S LABORATORIES LTD. (IN) | 2012-01-26 | — | — | WO | disclosed |