Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CACNA2D1 | P54289 | 2/20 | 0.62 |
| ▸ | CACNA1C | Q13936 | 2/20 | 0.62 |
| ▸ | CACNB3 | P54284 | 1/20 | 0.62 |
| ▸ | PGR | P06401 | 1/20 | 0.62 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.62 |
| ▸ | HTR2B | P41595 | 1/20 | 0.62 |
| ▸ | CACNA2D2 | Q9NY47 | 1/20 | 0.62 |
| ▸ | MGAM | O43451 | 1/20 | 0.38 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
| ▸ | SI | P14410 | 1/20 | 0.38 |
| ▸ | MGAM2 | Q2M2H8 | 1/20 | 0.38 |
| ▸ | TSHR | P16473 | 3/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | MMP1 | P03956 | 2/20 | 0.35 |
| ▸ | SLC7A5 | Q01650 | 1/20 | 0.34 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.33 |
| ▸ | SLC1A1 | P43005 | 1/20 | 0.33 |
| ▸ | CA12 | O43570 | 1/20 | 0.33 |
| ▸ | CA7 | P43166 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8141648 | 1.00 | CACNA2D1 (0.62) | CACNA2D1CACNA1CCACNB3PGRADRA1A | |
| SCHEMBL4336389 | 1.00 | CACNA2D1 (0.62) | CACNA2D1CACNA1CCACNB3PGRADRA1A | |
| Hydrochloric Acid SCHEMBL14108567 | 0.98 | CACNA2D1 (0.60) | CACNA2D1CACNA1CCACNB3PGRADRA1A | |
| Hydrochloric Acid SCHEMBL14108565 | 0.98 | CACNA2D1 (0.60) | CACNA2D1CACNA1CCACNB3PGRADRA1A | |
| SCHEMBL4880767 | 0.87 | CACNA2D1 (0.43) | CACNA2D1CACNA1CCACNB3PGRADRA1A | |
| SCHEMBL4297996 | 0.85 | MGAM (0.46) | CACNA2D1CACNA1CCACNB3PGRADRA1A | |
| SCHEMBL1419510 | 0.82 | CACNA2D1 (0.41) | CACNA2D1CACNA1CCACNB3PGRADRA1A | |
| SCHEMBL1419512 | 0.82 | CACNA2D1 (0.41) | CACNA2D1CACNA1CCACNB3PGRADRA1A | |
| SCHEMBL5003775 | 0.82 | CACNA2D1 (0.41) | CACNA2D1CACNA1CCACNB3PGRADRA1A | |
| SCHEMBL7980052 | 0.81 | CACNA2D1 (0.58) | CACNA2D1CACNA1CCACNB3PGRADRA1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009087650-A2 | A NOVEL PROCESS FOR SYNTHESIS OF PREGABALIN FROM SUBSTITUTED CYCLOPROPANE INTERMEDIATE AND A PROCESS FOR ENZYMATIC RESOLUTION OF RACEMIC PREGABALIN | V.B. MEDICARE PVT. LTD. (IN) | 2009-07-16 | — | — | WO | claimed |
| WO-2023115167-A1 | COMPOUNDS | Psylo Pty Ltd (AU) | 2023-06-29 | — | — | WO | disclosed |
| WO-2011071995-A2 | COMPOUNDS AND METHODS OF TREATING OCULAR DISORDERS | CASE WESTERN RESERVE UNIVERSITY (US) | 2011-06-16 | — | — | WO | disclosed |
| WO-2009087650-A2 | A NOVEL PROCESS FOR SYNTHESIS OF PREGABALIN FROM SUBSTITUTED CYCLOPROPANE INTERMEDIATE AND A PROCESS FOR ENZYMATIC RESOLUTION OF RACEMIC PREGABALIN | V.B. MEDICARE PVT. LTD. (IN) | 2009-07-16 | — | — | WO | disclosed |
| WO-2009044409-A2 | NOVEL RESOLUTION PROCESS FOR PREGABALIN | NATCO PHARMA LIMITED (IN) | 2009-04-09 | — | — | WO | disclosed |
| WO-2008127646-A2 | TRANSAMINASE-BASED PROCESSES FOR PREPARATION OF PREGABALIN | DSM IP ASSETS B.V. (NL) | 2008-10-23 | — | — | WO | disclosed |