Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARA | Q07869 | 10/20 | 0.53 |
| ▸ | PPARG | P37231 | 8/20 | 0.47 |
| ▸ | MRGPRX4 | Q96LA9 | 4/20 | 0.44 |
| ▸ | PPARD | Q03181 | 2/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
| ▸ | NPC1 | O15118 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | HPGD | P15428 | 1/20 | 0.40 |
| ▸ | HTT | P42858 | 1/20 | 0.40 |
| ▸ | RAB9A | P51151 | 1/20 | 0.40 |
| ▸ | MDM2 | Q00987 | 1/20 | 0.40 |
| ▸ | GPR55 | Q9Y2T6 | 1/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4336480 | 1.00 | PPARA (0.53) | PPARAPPARGMRGPRX4PPARDTDP1 | |
| SCHEMBL6651371 | 1.00 | PPARA (0.53) | PPARAPPARGMRGPRX4PPARDTDP1 | |
| SCHEMBL4332536 | 0.91 | PPARA (0.50) | PPARAPPARGMRGPRX4PPARDTDP1 | |
| SCHEMBL4332539 | 0.91 | PPARA (0.50) | PPARAPPARGMRGPRX4PPARDTDP1 | |
| SCHEMBL4339171 | 0.91 | PPARA (0.50) | PPARAPPARGMRGPRX4PPARDTDP1 | |
| SCHEMBL4335606 | 0.88 | PPARA (0.44) | PPARAPPARGMRGPRX4PPARD | |
| SCHEMBL4335605 | 0.88 | PPARA (0.44) | PPARAPPARGMRGPRX4PPARD | |
| SCHEMBL6651328 | 0.88 | PPARA (0.44) | PPARAPPARGMRGPRX4PPARD | |
| SCHEMBL13819776 | 0.87 | MRGPRX4 (0.59) | PPARAPPARGMRGPRX4SMN1; SMN2NPC1 | |
| SCHEMBL13819716 | 0.87 | MRGPRX4 (0.59) | PPARAPPARGMRGPRX4SMN1; SMN2NPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7544835-B2 | Carboxylic acid derivative and salt thereof | EISAI R&D MANAGEMENT CO., LTD. (JP) | 2009-06-09 | — | — | US | disclosed |
| EP-1380562-A1 | CARBOXYLIC ACID DERIVATIVE AND SALT THEREOF | Eisai Co., Ltd. (JP) | 2004-01-14 | — | — | EP | disclosed |