Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FGFR3 | P22607 | 20/20 | 0.67 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3314121 | 0.96 | FGFR3 (0.71) | FGFR3 | |
| SCHEMBL3316150 | 0.95 | FGFR3 (0.60) | FGFR3 | |
| SCHEMBL4336725 | 0.93 | FGFR3 (0.67) | FGFR3 | |
| SCHEMBL3314051 | 0.89 | FGFR3 (0.62) | FGFR3 | |
| SCHEMBL3314125 | 0.88 | FGFR3 (0.72) | FGFR3 | |
| SCHEMBL3316154 | 0.87 | FGFR3 (0.60) | FGFR3 | |
| SCHEMBL3318592 | 0.87 | FGFR3 (0.62) | FGFR3 | |
| SCHEMBL3318853 | 0.87 | FGFR3 (0.73) | FGFR3 | |
| SCHEMBL3317823 | 0.86 | FGFR3 (0.63) | FGFR3 | |
| SCHEMBL1126225 | 0.85 | FGFR3 (0.91) | FGFR3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009141386-A1 | DERIVATIVES OF QUINOLINES AND QUINOXALINES AS PROTEIN TYROSINE KINASE INHIBITORS | NOVARTIS AG (CH) | 2009-11-26 | — | — | WO | claimed |