⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL133747 | 0.77 | — | — | |
| SCHEMBL2355497 | 0.74 | — | — | |
| SCHEMBL135238 | 0.67 | — | — | |
| SCHEMBL104603 | 0.64 | CA1 (0.30) | — | |
| Hydroxyl Radical SCHEMBL28108301 | 0.64 | — | — | |
| SCHEMBL28418615 | 0.64 | HSD17B10 (0.47) | — | |
| SCHEMBL296293 | 0.64 | — | — | |
| SCHEMBL23448 | 0.64 | — | — | |
| SCHEMBL17586846 | 0.61 | HSD17B10 (0.45) | — | |
| SCHEMBL1727219 | 0.61 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 80 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-112513021-B | ROR gamma antagonist and application thereof in medicines | 广东东阳光药业有限公司 | 2023-06-27 | — | — | CN | claimed |
| CN-113072521-A | ROR gamma t inhibitor and application thereof in medicine | 广东东阳光药业有限公司 | 2021-07-06 | — | — | CN | claimed |
| CN-112513021-A | ROR gamma antagonist and application thereof in medicine | 广东东阳光药业有限公司 | 2021-03-16 | — | — | CN | claimed |
| CN-110903284-A | Fused tricyclic compound and application thereof in medicines | 广东东阳光药业有限公司 | 2020-03-24 | — | — | CN | claimed |
| WO-2020011147-A1 | RORγ ANTAGONIST AND APPLICATION THEREOF IN MEDICINE | SUNSHINE LAKE PHARMA CO., LTD. (CN) | 2020-01-16 | — | — | WO | claimed |
| EP-1549627-A1 | 1-PHENYLALKYL-PIPERAZINES | Recordati Ireland Limited (IE) | 2005-07-06 | — | — | EP | claimed |
| WO-2003106443-A1 | 1-PHENYLALKYL-PIPERAZINES | RECORDATI S.A. (CH) | 2003-12-24 | — | — | WO | claimed |
| US-6380197-B1 | FOR TREATING AND PREVENTING A PLETHORA OF DISEASES INCLUDING DIABETES | AVENTIS PHARMA S. A. (FR) | 2002-04-30 | — | — | US | claimed |
| EP-1001943-A1 | POLYHYDROXYALKYLPYRAZINE DERIVATIVES, PREPARATION AND MEDICINES CONTAINING THEM | Aventis Pharma S.A. (FR) | 2000-05-24 | — | — | EP | claimed |
| WO-1999003843-A1 | POLYHYDROXYALKYLPYRAZINE DERIVATIVES, PREPARATION AND MEDICINES CONTAINING THEM | RHONE-POULENC RORER S.A. (FR) | 1999-01-28 | — | — | WO | claimed |
| EP-0819982-A1 | Radiation-sensitive composition | Olin Microelectronic Chemicals, Inc. (US) | 1998-01-21 | — | — | EP | claimed |
| WO-1997045119-A1 | USE OF SUBSTANCE P ANTAGONISTS FOR TREATING SOCIAL PHOBIA | NOVARTIS AG (CH) | 1997-12-04 | — | — | WO | claimed |
| CN-118239939-A | Aryl-five-membered heterocycle-oxazoline compound and salt, preparation method and application thereof | 贵州大学 | 2024-06-25 | — | — | CN | disclosed |
| CN-113072521-B | ROR gamma t inhibitor and application thereof in medicines | 广东东阳光药业股份有限公司 | 2024-04-05 | — | — | CN | disclosed |
| WO-2023215694-A1 | SUBSTITUTED PYRIDINE-2,6-BIS(PHENYLENEPHENOLATE) COMPLEXES WITH ENHANCED SOLUBILITY THAT ARE USEFUL AS CATALYST COMPONENTS FOR OLEFIN POLYMERIZATION | EXXONMOBIL CHEMICAL PATENTS INC. (US) | 2023-11-09 | — | — | WO | disclosed |
| CN-112513021-B | ROR gamma antagonist and application thereof in medicines | 广东东阳光药业有限公司 | 2023-06-27 | — | — | CN | disclosed |
| US-4783462-A | 3(2H)pyridazinone, and anti-allergic agent containing it | NISSAN CHEMICAL INDUSTRIES LTD. (JP) | 1988-11-08 | — | — | US | disclosed |
| EP-0193853-A2 | 3(2H)pyridazinone, process for its preparation and anti-allergic agent containing it | NISSAN CHEMICAL INDUSTRIES LTD. (JP) | 1986-09-10 | — | — | EP | disclosed |
| EP-0185589-A1 | Derivatives of methylene bis-phosphonic acids, their preparation and pharmaceutical compositions containing them | RHONE-POULENC SANTE (FR) | 1986-06-25 | — | — | EP | disclosed |
| EP-0153678-A1 | Cinnamic acid derivatives, processes for the preparation thereof and pharmaceutical compositions | Tanabe Seiyaku Co., Ltd. (JP) | 1985-09-04 | — | — | EP | disclosed |