Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4350818 | 0.94 | PDE4B (0.58) | PDE4BADORA1 | |
| SCHEMBL583313 | 0.92 | PDE4B (0.70) | PDE4BADORA1 | |
| SCHEMBL583135 | 0.90 | PDE4B (0.77) | PDE4B | |
| SCHEMBL583156 | 0.89 | PDE4B (0.77) | PDE4B | |
| SCHEMBL583438 | 0.88 | PDE4B (0.65) | PDE4BADORA1 | |
| SCHEMBL583410 | 0.88 | PDE4B (0.83) | PDE4BADORA1 | |
| SCHEMBL582853 | 0.87 | PDE4B (0.82) | PDE4B | |
| SCHEMBL4345701 | 0.87 | PDE4B (0.63) | PDE4BADORA1 | |
| SCHEMBL4341428 | 0.87 | PDE4B (0.63) | PDE4BADORA1 | |
| SCHEMBL583383 | 0.86 | PDE4B (0.62) | PDE4BADORA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1539753-B1 | PYRAZOLO(3,4-B)PYRIDINE COMPOUNDS, AND THEIR USE AS PHOSPHODIESTERASE INHIBITORS | GLAXO GROUP LTD (GB) | 2009-09-09 | — | — | EP | disclosed |