SCHEMBL4337864

SCHEMBL4337864

F[C]1CC(F)C1(F)F

nearest known ligand 0.00

⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3367777 0.71
SCHEMBL7094439 0.67
SCHEMBL3284420 0.67
SCHEMBL7466796 0.67
SCHEMBL7466792 0.67
SCHEMBL6411877 0.63
SCHEMBL4865879 0.60
SCHEMBL250936 0.56
SCHEMBL4595569 0.56
SCHEMBL2029571 0.56

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 78 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-4391607-A Dyeing process and printing process using reactive dyestuffs BAYER AKTIENGESELLSCHAFT (DE) 1983-07-05 US claimed
EP-2970277-B1 IMIDAZO(4,5-B) PYRIDIN-2-YL AMIDES AS KV7 CHANNEL ACTIVATORS KNOPP BIOSCIENCES LLC (US) 2021-07-28 EP disclosed
US-20190002464-A1 IMIDAZO[4,5-B]PYRIDIN-2-YL AMIDES AS KV7 CHANNEL ACTIVATORS CHANNEL BIOSCIENCES, LLC 2019-01-03 US disclosed
US-10106536-B2 Imidazo(4,5-B) pyridin-2-yl amides as KV7 channel activators KNOPP BIOSCIENCES LLC (US) 2018-10-23 US disclosed
US-20170240547-A1 IMIDAZO(4,5-B) PYRIDIN-2-YL AMIDES AS KV7 CHANNEL ACTIVATORS CHANNEL BIOSCIENCES, LLC 2017-08-24 US disclosed
US-9650376-B2 Imidazo(4,5-B) pyridin-2-yl amides as KV7 channel activators KNOPP BIOSCIENCES LLC (US) 2017-05-16 US disclosed
US-20160145222-A1 Methods for Controlling Pests in Soybean BASF SE (DE) 2016-05-26 US disclosed
US-9268225-B2 Composition, resist pattern-forming method, compound, method for production of compound, and polymer JSR CORPORATION (JP) 2016-02-23 US disclosed
US-20160031875-A1 IMIDAZO(4,5-B) PYRIDIN-2-YL AMIDES AS KV7 CHANNEL ACTIVATORS CHANNEL BIOSCIENCES, LLC 2016-02-04 US disclosed
EP-2970277-A2 IMIDAZO(4,5-B) PYRIDIN-2-YL AMIDES AS KV7 CHANNEL ACTIVATORS Knopp Biosciences LLC (US) 2016-01-20 EP disclosed
US-4304567-A Process for the pad-dyeing of textile webs of cellulose fibers HOECHST AKTIENGESELLSCHAFT (DE) 1981-12-08 US disclosed
US-4297101-A Process for the dyeing of synthetic polyamide fibers with reactive dyes according to the batchwise exhaustion method HOECHST AKTIENGESELLSCHAFT (DE) 1981-10-27 US disclosed
US-4277246-A AQUEOUS SOLUTION, NEUTRAL ELECTROLYTE HOECHST AKTIENGESELLSCHAFT (DE) 1981-07-07 US disclosed
US-4264321-A CONTACTING WITH STEAM AT HIGH PRESSURE WITHOUT THE ADDITION OF ALKALI HOECHST AKTIENGESELLSCHAFT (DE) 1981-04-28 US disclosed
US-4242090-A Process for the continuous dyeing of textile webs of cellulose fibers with reactive dyes HOECHST AKTIENGESELLSCHAFT (DE) 1980-12-30 US disclosed
US-4242091-A Process for the continuous dyeing of textile webs pre-heated with infra-red or micro-waves HOECHST AKTIENGESELLSCHAFT (DE) 1980-12-30 US disclosed
US-4198204-A ADDING AN ANIONIC AND/OR NONIONIC ALIPHATIC SURFACTANT HOECHST AKTIENGESELLSCHAFT (DE) 1980-04-15 US disclosed
US-4184842-A Continuous dyeing of cellulose fibers with reactive dyestuffs HOECHST AKTIENGESELLSCHAFT (DE) 1980-01-22 US disclosed
US-4139344-A Process for the continuous dyeing of wool HOECHST AKTIENGESELLSCHAFT (DE) 1979-02-13 US disclosed
US-4008261-A Method of preparing phosphonium siloxanes and products thereof DOW CORNING CORPORATION (US) 1977-02-15 US disclosed