Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | F2R | P25116 | 14/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
| ▸ | PTGS1 | P23219 | 4/20 | 0.32 |
| ▸ | PTGS2 | P35354 | 4/20 | 0.32 |
| ▸ | ALOX5 | P09917 | 2/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Bromide SCHEMBL5585079 | 0.99 | F2R (0.35) | F2RMEN1KMT2APTGS1PTGS2 | |
| SCHEMBL14346311 | 0.82 | F2R (0.47) | F2RMEN1KMT2APTGS1PTGS2 | |
| Bromide SCHEMBL4344870 | 0.81 | F2R (0.46) | F2RMEN1KMT2APTGS1PTGS2 | |
| SCHEMBL6366000 | 0.75 | F2R (0.38) | F2R | |
| Bromide SCHEMBL4333522 | 0.75 | F2R (0.38) | F2R | |
| SCHEMBL1189832 | 0.71 | MEN1 (0.43) | F2RMEN1KMT2APTGS1PTGS2 | |
| SCHEMBL13588612 | 0.71 | MEN1 (0.43) | F2RMEN1KMT2APTGS1PTGS2 | |
| SCHEMBL2083911 | 0.71 | F2R (0.35) | F2R | |
| Bromide SCHEMBL6746455 | 0.70 | F2R (0.65) | F2RMEN1KMT2A | |
| SCHEMBL3969535 | 0.70 | F2R (0.35) | F2R |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1391456-B1 | 2-IMINOIMIDAZOLE DERIVATIVES | EISAI R&D MAN CO LTD (JP) | 2009-07-22 | — | — | EP | disclosed |
| US-7304083-B2 | 2-iminoimidazole derivatives (2) | EISAI R&D MANAGEMENT CO., LTD. (JP) | 2007-12-04 | — | — | US | disclosed |
| US-7304083-B2 | 2-iminoimidazole derivatives (2) | EISAI R&D MANAGEMENT CO., LTD. (JP) | 2007-12-04 | — | — | US | disclosed |
| EP-1391456-A1 | 2-IMINOIMIDAZOLE DERIVATIVE (2) | Eisai Co., Ltd. (JP) | 2004-02-25 | — | — | EP | disclosed |