Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | F2R | P25116 | 10/20 | 0.43 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.39 |
| ▸ | MAOB | P27338 | 4/20 | 0.38 |
| ▸ | BCHE | P06276 | 2/20 | 0.38 |
| ▸ | MAOA | P21397 | 2/20 | 0.38 |
| ▸ | ACHE | P22303 | 2/20 | 0.38 |
| ▸ | GAA | P10253 | 1/20 | 0.34 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.34 |
| ▸ | HSP90AB1 | P08238 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13750972 | 1.00 | F2R (0.43) | F2RCYP3A4MAOBBCHEMAOA | |
| Bromide SCHEMBL4329592 | 0.99 | F2R (0.42) | F2RCYP3A4MAOBBCHEMAOA | |
| SCHEMBL4335548 | 0.95 | F2R (0.44) | F2RCYP3A4MAOBBCHEMAOA | |
| SCHEMBL13750959 | 0.95 | F2R (0.44) | F2RCYP3A4MAOBBCHEMAOA | |
| Bromide SCHEMBL4330579 | 0.94 | F2R (0.43) | F2RCYP3A4MAOBBCHEMAOA | |
| SCHEMBL4337619 | 0.89 | F2R (0.46) | F2RCYP3A4MAOBBCHEMAOA | |
| SCHEMBL13750962 | 0.89 | F2R (0.46) | F2RCYP3A4MAOBBCHEMAOA | |
| SCHEMBL4345531 | 0.89 | F2R (0.48) | F2RMAOBBCHEMAOAACHE | |
| SCHEMBL13751025 | 0.89 | F2R (0.48) | F2RMAOBBCHEMAOAACHE | |
| Bromide SCHEMBL4334113 | 0.88 | F2R (0.45) | F2RCYP3A4MAOBBCHEMAOA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1386912-B1 | CYCLIC AMIDINE DERIVATIVE | EISAI R&D MAN CO LTD (JP) | 2009-03-18 | — | — | EP | claimed |