⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12658620 | 0.97 | PAOX (1.00) | — | |
| SCHEMBL3318566 | 0.97 | PAOX (1.00) | — | |
| SCHEMBL9623780 | 0.97 | PAOX (1.00) | — | |
| SCHEMBL16297742 | 0.97 | PAOX (1.00) | — | |
| SCHEMBL13082344 | 0.97 | PAOX (1.00) | — | |
| SCHEMBL23872982 | 0.97 | PAOX (1.00) | — | |
| Hydrochloric Acid SCHEMBL11569445 | 0.97 | — | — | |
| SCHEMBL806164 | 0.97 | — | — | |
| SCHEMBL18533504 | 0.97 | PAOX (1.00) | — | |
| SCHEMBL18726287 | 0.97 | PAOX (1.00) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 158 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022247065-A1 | SYNTHESIS METHOD FOR PENTOXIFYLLINE | 海南通用康力制药有限公司 | 2022-12-01 | — | — | WO | claimed |
| CN-113214259-B | Synthesis method of pentoxifylline | 海南通用康力制药有限公司 | 2022-06-10 | — | — | CN | claimed |
| CN-113214259-A | Synthesis method of pentoxifylline | 海南通用康力制药有限公司 | 2021-08-06 | — | — | CN | claimed |
| EP-0731648-B1 | FLAVOURING COMPOSITIONS AND METHOD | FIRMENICH & CIE (CH) | 2003-03-26 | — | — | EP | claimed |
| CN-118652255-B | Process improvement method of pentoxifylline | 广州市桐晖药业有限公司 | 2024-10-15 | — | — | CN | disclosed |
| CN-118652255-A | Process improvement method of pentoxifylline | 广州市桐晖药业有限公司 | 2024-09-17 | — | — | CN | disclosed |
| US-12043599-B2 | Herbicidal compounds | SYNGENTA PARTICIPATIONS AG (CH) | 2024-07-23 | — | — | US | disclosed |
| CN-117466894-A | Preparation method of pentoxifylline | 河北一品生物医药有限公司 | 2024-01-30 | — | — | CN | disclosed |
| WO-2023225661-A1 | MACROCYCLIC IMMUNOMODULATORS | BRISTOL-MYERS SQUIBB COMPANY (US) | 2023-11-23 | — | — | WO | disclosed |
| WO-2023154818-A1 | MUCOSAL ADMINISTRATION METHODS AND FORMULATIONS | MODERNATX, INC. (US) | 2023-08-17 | — | — | WO | disclosed |
| WO-2023076598-A1 | LIPID AMINES | MODERNATX, INC. (US) | 2023-05-04 | — | — | WO | disclosed |
| WO-2022247065-A1 | SYNTHESIS METHOD FOR PENTOXIFYLLINE | 海南通用康力制药有限公司 | 2022-12-01 | — | — | WO | disclosed |
| US-4151351-A | PROSTAGLANDINS, ANTIINFLAMMATORY | THE UPJOHN COMPANY (US) | 1979-04-24 | — | — | US | disclosed |
| US-4131738-A | 6-Hydroxy-PGE1 compounds | THE UPJOHN COMPANY (US) | 1978-12-26 | — | — | US | disclosed |
| US-4128713-A | 6,7-Didehydro-PGI1 compounds | THE UPJOHN COMPANY (US) | 1978-12-05 | — | — | US | disclosed |
| US-4126744-A | PROSTACYCLIN, MUSCLE STIMULANTS, PLATELET AGGREGATION INHIBITORS | THE UPJOHN COMPANY (US) | 1978-11-21 | — | — | US | disclosed |
| US-4112224-A | PROSTAGLANDIN | THE UPJOHN COMPANY (US) | 1978-09-05 | — | — | US | disclosed |
| US-4109082-A | PROSTACYCLIN ANALOGS; SMOOTH MUSCLE STIMULATORS | THE UPJOHN COMPANY (US) | 1978-08-22 | — | — | US | disclosed |
| US-4100192-A | Inter-phenylene-PG amides | THE UPJOHN COMPANY (US) | 1978-07-11 | — | — | US | disclosed |
| US-4097489-A | PROSTAGLANDINS | THE UPJOHN COMPANY (US) | 1978-06-27 | — | — | US | disclosed |