Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | F2R | P25116 | 10/20 | 0.58 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.41 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.41 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | RECQL | P46063 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL5585192 | 0.99 | F2R (0.57) | F2RALOX5PTGS1PTGS2CYP3A4 | |
| SCHEMBL5585086 | 0.91 | F2R (0.55) | F2RALOX5PTGS1PTGS2CYP3A4 | |
| SCHEMBL6366732 | 0.91 | F2R (0.52) | F2RALOX5PTGS1PTGS2CYP3A4 | |
| Bromide SCHEMBL4340078 | 0.90 | F2R (0.54) | F2RALOX5PTGS1PTGS2CYP3A4 | |
| Bromide SCHEMBL4340417 | 0.90 | F2R (0.51) | F2RALOX5PTGS1PTGS2CYP3A4 | |
| SCHEMBL14346324 | 0.89 | F2R (0.64) | F2RKMT2AMEN1GAA | |
| Bromide SCHEMBL4347358 | 0.88 | F2R (0.63) | F2RLMNAKMT2AMEN1 | |
| SCHEMBL6360881 | 0.87 | F2R (0.65) | F2RLMNAKMT2AMEN1 | |
| Bromide SCHEMBL4340619 | 0.86 | F2R (0.64) | F2RLMNAKMT2AMEN1 | |
| SCHEMBL6366900 | 0.86 | F2R (0.55) | F2RRECQLKMT2AMEN1GAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1391456-B1 | 2-IMINOIMIDAZOLE DERIVATIVES | EISAI R&D MAN CO LTD (JP) | 2009-07-22 | — | — | EP | disclosed |
| US-7304083-B2 | 2-iminoimidazole derivatives (2) | EISAI R&D MANAGEMENT CO., LTD. (JP) | 2007-12-04 | — | — | US | disclosed |