SCHEMBL43394

SCHEMBL43394

NC(Cc1ccccc1)C(O)CC(=O)O

nearest known ligand 0.55

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CPA1 P15085 2/20 0.55
CPB1 P15086 1/20 0.55
CPA3 P15088 1/20 0.55
CPB2 Q96IY4 1/20 0.55
SLC15A1 P46059 2/20 0.54
ALPI P09923 1/20 0.53
PKM P14618 1/20 0.53
PTGS1 P23219 1/20 0.53
XIAP P98170 1/20 0.53
SLC7A5 Q01650 1/20 0.53
CSNK1E P49674 1/20 0.53
EPHX1 P07099 1/20 0.52
SLC1A3 P43003 2/20 0.49
SLC1A2 P43004 2/20 0.49
SLC1A1 P43005 2/20 0.49
LTA4H P09960 1/20 0.47
CYP1A2 P05177 1/20 0.47
LAP3 P28838 5/20 0.47
ANPEP P15144 3/20 0.47
RNPEP Q9H4A4 1/20 0.47

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL21689939 1.00 CPA1 (0.55) CPA1CPB1CPA3CPB2SLC15A1
SCHEMBL3495957 1.00 CPA1 (0.55) CPA1CPB1CPA3CPB2SLC15A1
SCHEMBL10657726 0.85 CPA1 (0.58) CPA1CPB1CPA3CPB2SLC15A1
SCHEMBL7276908 0.85 CPA1 (0.58) CPA1CPB1CPA3CPB2SLC15A1
SCHEMBL7322202 0.85 CPA1 (0.58) CPA1CPB1CPA3CPB2SLC15A1
SCHEMBL197907 0.82 EPHX1 (0.64) CPA1CPB1CPA3CPB2SLC15A1
SCHEMBL287736 0.82 EPHX1 (0.64) CPA1CPB1CPA3CPB2SLC15A1
SCHEMBL123055 0.82 EPHX1 (0.64) CPA1CPB1CPA3CPB2SLC15A1
SCHEMBL10433814 0.82 CSNK1E (0.58) CPA3SLC15A1ALPIPKMPTGS1
SCHEMBL6425554 0.82 EPHX1 (0.62) SLC15A1ALPIPKMPTGS1XIAP

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Appears in 2423 patents — a generic fragment claimed broadly, so it's down-weighted as IP noise. Top by claim status then date:

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20140057850-A1 PEPTIDE FOR USE IN THE TREATMENT OF SKIN CONDITIONS ORGANOBALANCE GMBH (DE) 2014-02-27 US claimed
EP-0211744-B1 PEPTIDIC AMINO-ALCOHOL DERIVATIVES CONTAINING A TETRA-SUBSTITUTED CARBON ATOM, INHIBITORS OF RENIN AND OF ACID PROTEASES, PREPARATION PROCESS AND PHARMACEUTICAL COMPOSITIONS SANOFI (FR) 1991-12-04 EP claimed
WO-2026085582-A1 PROTEIN CAGES THE UNIVERSITY OF SYDNEY (AU) 2026-04-30 WO disclosed
EP-4731641-A1 BIO-ENGINEERED FLAGELLIN-DERIVED SCAFFOLD BACKBONE AND USES THEREOF EpitogenX Limited (GB) 2026-04-29 EP disclosed
US-20260085104-A1 METHODS OF DETECTING IMMUNE CELLS BIOSCEPTRE AUST PTY LTD (AU) 2026-03-26 US disclosed
EP-4710935-A2 NOVEL IMMUNOTHERAPEUTIC COMPOSITION AND USES THEREOF Aravax Pty Ltd (AU) 2026-03-18 EP disclosed
EP-4705440-A1 NAMPT FUSION PROTEINS Monash University (AU) 2026-03-11 EP disclosed
US-20260055150-A1 GRAIL-1 PEPTIDE PRODUCTS AND METHODS UNIV MICHIGAN (US) 2026-02-26 US disclosed
US-20260049121-A1 SUPRAMOLECULAR HIGH AFFINITY PROTEIN-BINDING SYSTEM FOR PURIFICATION OF BIOMACROMOLECULES UNIV JOHNS HOPKINS (US) 2026-02-19 US disclosed
US-20260022147-A1 PLACENTA EXPRESSED PROTEINS FOR USE IN THE TREATMENT OF TENDON INJURY UNIV COLLEGE CORK NATIONAL UNIV OF IRELAND CORK (IE) 2026-01-22 US disclosed
EP-4680108-A1 PEPTIDE MULTIMER PRODUCTS AND METHODS The Regents of The University of Michigan (US) 2026-01-21 EP disclosed
EP-0292800-A2 Amino acid derivatives MERCK PATENT GmbH (DE) 1988-11-30 EP disclosed
EP-0286813-A2 Renin-inhibiting amino acid derivatives MERCK PATENT GmbH (DE) 1988-10-19 EP disclosed
EP-0272444-A2 Renin-inhibiting peptides MERCK PATENT GmbH (DE) 1988-06-29 EP disclosed
US-4746648-A HYPOTENSIVE, ANTIULCER Sanofi, Institut National de la Recherche Medicale (FR) 1988-05-24 US disclosed
EP-0262318-A2 Renin-inhibiting amino acid derivatives MERCK PATENT GmbH (DE) 1988-04-06 EP disclosed
US-4725580-A ARTERIAL TENSION SANOFI (FR) 1988-02-16 US disclosed
US-4721776-A Amino acid derivatives MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) 1988-01-26 US disclosed
EP-0249096-A2 Renin-inhibiting amino acid derivatives MERCK PATENT GmbH (DE) 1987-12-16 EP disclosed
EP-0222283-A2 Amino-acid derivatives MERCK PATENT GmbH (DE) 1987-05-20 EP disclosed