Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMYD2 | Q9NRG4 | 3/20 | 0.37 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.37 |
| ▸ | HTT | P42858 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | LTB4R | Q15722 | 3/20 | 0.33 |
| ▸ | FGFR1 | P11362 | 1/20 | 0.33 |
| ▸ | SRC | P12931 | 1/20 | 0.33 |
| ▸ | PDK2 | Q15119 | 2/20 | 0.32 |
| ▸ | SOAT1 | P35610 | 1/20 | 0.32 |
| ▸ | MPO | P05164 | 1/20 | 0.32 |
| ▸ | PPARA | Q07869 | 1/20 | 0.32 |
| ▸ | KCNH3 | Q9ULD8 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7037378 | 1.00 | SMYD2 (0.37) | SMYD2CYP3A4HTTSMN1; SMN2KDM4E | |
| SCHEMBL17641091 | 1.00 | SMYD2 (0.37) | SMYD2CYP3A4HTTSMN1; SMN2KDM4E | |
| SCHEMBL30438065 | 1.00 | SMYD2 (0.37) | SMYD2CYP3A4HTTSMN1; SMN2KDM4E | |
| SCHEMBL4823593 | 1.00 | SMYD2 (0.37) | SMYD2CYP3A4HTTSMN1; SMN2KDM4E | |
| SCHEMBL18257718 | 1.00 | SMYD2 (0.37) | SMYD2CYP3A4HTTSMN1; SMN2KDM4E | |
| SCHEMBL4823073 | 1.00 | SMYD2 (0.37) | SMYD2CYP3A4HTTSMN1; SMN2KDM4E | |
| SCHEMBL25357815 | 1.00 | SMYD2 (0.37) | SMYD2CYP3A4HTTSMN1; SMN2KDM4E | |
| SCHEMBL31528885 | 1.00 | SMYD2 (0.37) | SMYD2CYP3A4HTTSMN1; SMN2KDM4E | |
| SCHEMBL1765926 | 1.00 | SMYD2 (0.37) | SMYD2CYP3A4HTTSMN1; SMN2KDM4E | |
| SCHEMBL639531 | 0.98 | SMYD2 (0.37) | SMYD2CYP3A4HTTSMN1; SMN2KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009133686-A1 | MEDICAMENTS FOR TREATING ALZHEIMER'S DISEASE | 有限会社アンティアンティ (JP) | 2009-11-05 | — | — | WO | disclosed |