Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PLAU | P00749 | 1/20 | 0.39 |
| ▸ | PPARG | P37231 | 3/20 | 0.39 |
| ▸ | PPARA | Q07869 | 3/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4339657 | 1.00 | PLAU (0.39) | PLAUPPARGPPARA | |
| SCHEMBL4339256 | 0.94 | PPARG (0.46) | PPARGPPARA | |
| SCHEMBL4342511 | 0.92 | PPARA (0.45) | PLAUPPARGPPARA | |
| SCHEMBL4329078 | 0.92 | PPARA (0.45) | PLAUPPARGPPARA | |
| SCHEMBL13810957 | 0.88 | TSHR (0.52) | PLAUPPARGPPARA | |
| SCHEMBL4337158 | 0.88 | TSHR (0.52) | PLAUPPARGPPARA | |
| SCHEMBL4334159 | 0.88 | MEN1 (0.44) | PLAUPPARGPPARA | |
| SCHEMBL4334148 | 0.88 | MEN1 (0.44) | PLAUPPARGPPARA | |
| SCHEMBL4328125 | 0.88 | TSHR (0.40) | PPARGPPARA | |
| SCHEMBL4339680 | 0.86 | GAA (0.45) | PLAUPPARGPPARA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7544835-B2 | Carboxylic acid derivative and salt thereof | EISAI R&D MANAGEMENT CO., LTD. (JP) | 2009-06-09 | — | — | US | disclosed |