Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1363559 | 0.94 | PDE4B (0.60) | PDE4B | |
| SCHEMBL4937412 | 0.86 | PDE4B (0.58) | PDE4B | |
| SCHEMBL4937373 | 0.85 | PDE4B (0.57) | PDE4BPDE7A | |
| SCHEMBL8281071 | 0.85 | PDE4B (0.62) | PDE4BPDE7A | |
| SCHEMBL1363114 | 0.83 | PDE4B (0.70) | PDE4B | |
| SCHEMBL221173 | 0.83 | PDE4B (0.61) | PDE4BPDE7A | |
| SCHEMBL1362494 | 0.81 | PDE4B (0.59) | PDE4B | |
| SCHEMBL4937074 | 0.81 | PDE4B (0.59) | PDE4B | |
| SCHEMBL4334216 | 0.81 | PDE4B (0.73) | PDE4B | |
| SCHEMBL4934271 | 0.80 | PDE4B (0.72) | PDE4B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1539753-B1 | PYRAZOLO(3,4-B)PYRIDINE COMPOUNDS, AND THEIR USE AS PHOSPHODIESTERASE INHIBITORS | GLAXO GROUP LTD (GB) | 2009-09-09 | — | — | EP | disclosed |