Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP1A2 | P05177 | 2/20 | 0.51 |
| ▸ | PPARG | P37231 | 2/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.46 |
| ▸ | GRM2 | Q14416 | 5/20 | 0.44 |
| ▸ | SIRT2 | Q8IXJ6 | 4/20 | 0.44 |
| ▸ | POLB | P06746 | 1/20 | 0.44 |
| ▸ | FASN | P49327 | 1/20 | 0.44 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.43 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.41 |
| ▸ | CDC25B | P30305 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8398786 | 1.00 | CYP1A2 (0.51) | CYP1A2PPARGALDH1A1GRM2SIRT2 | |
| SCHEMBL8394045 | 1.00 | CYP1A2 (0.51) | CYP1A2PPARGALDH1A1GRM2SIRT2 | |
| SCHEMBL18979113 | 1.00 | CYP1A2 (0.51) | CYP1A2PPARGALDH1A1GRM2SIRT2 | |
| SCHEMBL18981127 | 1.00 | CYP1A2 (0.51) | CYP1A2PPARGALDH1A1GRM2SIRT2 | |
| SCHEMBL7153568 | 0.98 | CYP1A2 (0.49) | CYP1A2PPARGALDH1A1GRM2SIRT2 | |
| SCHEMBL8394086 | 0.93 | CYP1A2 (0.42) | CYP1A2PPARGGRM2SIRT2POLB | |
| SCHEMBL8396285 | 0.85 | KAT2A (0.39) | CYP1A2SIRT2POLBFASNPTPN1 | |
| SCHEMBL19729125 | 0.83 | CYP1A2 (0.33) | CYP1A2PPARGGRM2SIRT2POLB | |
| SCHEMBL7024404 | 0.81 | CYP1A2 (0.67) | CYP1A2PPARGALDH1A1GRM2SIRT2 | |
| SCHEMBL20803560 | 0.81 | CYP1A2 (0.67) | CYP1A2PPARGALDH1A1GRM2SIRT2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20090053804-A1 | METHODS OF REDUCING INTRACELLULAR FATS FROM MAMMALIAN CELLS | VESTA THERAPEUTICS, INC. | 2009-02-26 | — | — | US | disclosed |