SCHEMBL434017

SCHEMBL434017

C1=CNN=CC1

nearest known ligand 0.00

⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL12028061 0.75
SCHEMBL8658 0.67
SCHEMBL2500362 0.61
SCHEMBL12028059 0.61
SCHEMBL12028098 0.59
SCHEMBL18653951 0.57
SCHEMBL22562861 0.57
SCHEMBL29221443 0.57
SCHEMBL9472 0.54
SCHEMBL12028057 0.53

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 309 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4598586-A1 DRUG LINKERS AND ANTIBODY CONJUGATES THEREOF Ambrx, Inc. (US) 2025-08-13 EP claimed
WO-2024241086-A1 PEGYLATED BOVINE INTERFERON LAMBDA AND METHODS OF USE THEREOF AMBRX, INC. (US) 2024-11-28 WO claimed
WO-2024215515-A1 DRUG LINKERS AND ANTIBODY CONJUGATES THEREOF AMBRX, INC. (US) 2024-10-17 WO claimed
WO-2024178310-A1 TROP2-DIRECTED ANTIBODY-DRUG CONJUGATES AND USES THEREOF AMBRX, INC. (US) 2024-08-29 WO claimed
WO-2024178360-A2 AURISTATIN ANALOGS AND ANTIBODY CONJUGATES THEREOF AMBRX, INC. (US) 2024-08-29 WO claimed
WO-2024077277-A1 DRUG LINKERS AND ANTIBODY CONJUGATES THEREOF AMBRX, INC. (US) 2024-04-11 WO claimed
US-20230313180-A1 MULTIMERIC ANTIBODY PLATFORM AND METHODS OF MAKING AND USING MULTIMERIC ANTIBODY PLATFORM OREGON STATE UNIVERSITY (US) 2023-10-05 US claimed
CN-115417821-A Substituted 1, 4-dihydropyridazine derivative and preparation and application thereof 湖北科技学院 2022-12-02 CN claimed
US-10851192-B2 Dihydropyridazine-based antioxidants and uses thereof ARIZONA BOARD OF REGENTS ON BEHALF OF THE UNIVERSITY OF ARIZONA (US) 2020-12-01 US claimed
CN-111848526-A Polysubstituted 1, 4-dihydropyridazine and pyridazine derivatives and synthetic method thereof 南京工业大学 2020-10-30 CN claimed
WO-2003099284-A1 AMINO-PYRIDINE, -PYRIDINE AND PYRIDAZINE DERIVATIVES FOR USE AS VANILLOID RECEPTOR LIGANDS FOR THE TREATMENT OF PAIN AMGEN INC. (US) 2003-12-04 WO claimed
US-20030195201-A1 Vanilloid receptor ligands and their use in treatments AMGEN INC. 2003-10-16 US claimed
WO-2003049702-A2 VANILLOID RECEPTOR LIGANDS AND THEIR USE IN TREATMENTS AMGEN INC. (US) 2003-06-19 WO claimed
EP-0173205-A2 1,4-Dihydropyridazine derivatives, process for their preparation and their use in medicaments BAYER AG (DE) 1986-03-05 EP claimed
US-4348395-A 1,4-Dihydropyridazine compounds BAYER AKTIENGESELLSCHAFT (DE) 1982-09-07 US claimed
EP-0001108-B1 1,4-DIHYDROPYRIDAZINES, PROCESS FOR THEIR PREPARATION AND THEIR USE IN PHARMACEUTICALS BAYER AG (DE) 1981-04-29 EP claimed
EP-0001439-B1 1-N-SUBSTITUTED 1.4-DIHYDROPYRIDAZINE DERIVATIVES, METHOD FOR THEIR PREPARATION AND THEIR USE FOR PHARMACEUTICALS BAYER AG (DE) 1981-01-28 EP claimed
EP-0001439-A1 1-N-substituted 1.4-dihydropyridazine derivatives, method for their preparation and their use for pharmaceuticals BAYER AG (DE) 1979-04-18 EP claimed
EP-0001108-A1 1,4-Dihydropyridazines, process for their preparation and their use in pharmaceuticals BAYER AG (DE) 1979-03-21 EP claimed
US-4008239-A Preparation of 4-(3-nitrophenyl)pyridine STERLING DRUG INC. (US) 1977-02-15 US claimed