Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 7/20 | 0.56 |
| ▸ | NPC1 | O15118 | 7/20 | 0.43 |
| ▸ | RAB9A | P51151 | 7/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.43 |
| ▸ | NFKB1 | P19838 | 2/20 | 0.43 |
| ▸ | NFKB2 | Q00653 | 2/20 | 0.43 |
| ▸ | RELA | Q04206 | 2/20 | 0.43 |
| ▸ | TP53 | P04637 | 2/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.43 |
| ▸ | TSHR | P16473 | 1/20 | 0.43 |
| ▸ | CASP3 | P42574 | 1/20 | 0.43 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.43 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
| ▸ | HTT | P42858 | 2/20 | 0.39 |
| ▸ | USP2 | O75604 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
| ▸ | ATM | Q13315 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2944372 | 0.78 | SMN1; SMN2 (0.59) | SMN1; SMN2NPC1RAB9AKDM4ENFKB1 | |
| SCHEMBL2939976 | 0.78 | SMN1; SMN2 (0.56) | SMN1; SMN2NPC1RAB9AKDM4ENFKB1 | |
| SCHEMBL4340675 | 0.75 | SMN1; SMN2 (0.55) | SMN1; SMN2NPC1RAB9AKDM4ENFKB1 | |
| SCHEMBL2945692 | 0.72 | SMN1; SMN2 (0.74) | SMN1; SMN2NPC1RAB9AKDM4ENFKB1 | |
| SCHEMBL13744688 | 0.71 | SMN1; SMN2 (0.59) | SMN1; SMN2NPC1RAB9AKDM4ETP53 | |
| SCHEMBL13515748 | 0.70 | SMN1; SMN2 (0.56) | SMN1; SMN2NPC1RAB9AKDM4ENFKB1 | |
| SCHEMBL4312968 | 0.70 | KMT2A (0.62) | SMN1; SMN2NPC1RAB9AKDM4ENFKB1 | |
| SCHEMBL4312980 | 0.70 | KMT2A (0.62) | SMN1; SMN2NPC1RAB9AKDM4ENFKB1 | |
| SCHEMBL13744493 | 0.69 | SMN1; SMN2 (0.59) | SMN1; SMN2NPC1RAB9AKDM4ENFKB1 | |
| Hydrochloric Acid SCHEMBL2943708 | 0.69 | SMN1; SMN2 (0.58) | SMN1; SMN2NPC1RAB9AKDM4ENFKB1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20090209511-A1 | Benzofuran Derivatives | KAWAGUCHI TAKAYUKI | 2009-08-20 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090209511-A1 | Benzofuran Derivatives | F12, F2, F3 | SMN1; SMN2 3067/4885NPC1 3431/4885RAB9A 4600/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.