Known targets — ChEMBL curated mechanism
MMP1MMP13MMP7MMP8polrplArplBrplCrplDrplErplFrplJrplKrplLrplMrplNrplOrplPrplQrplRrplSrplTrplUrplVrplWrplXrplYrpmArpmBrpmCrpmDrpmErpmFrpmGrpmHrpmIrpmJrpsArpsBrpsCrpsDrpsErpsFrpsGrpsHrpsIrpsJrpsKrpsLrpsMrpsNrpsOrpsPrpsQrpsRrpsSrpsTrpsUykgMykgO
The experimentally established mechanism targets of Alcohol. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ESR1 | P03372 | 1/20 | 0.35 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.35 |
| ▸ | MGAM | O43451 | 1/20 | 0.35 |
| ▸ | CA1 | P00915 | 2/20 | 0.35 |
| ▸ | CA2 | P00918 | 2/20 | 0.35 |
| ▸ | CA4 | P22748 | 2/20 | 0.35 |
| ▸ | CA12 | O43570 | 1/20 | 0.35 |
| ▸ | CA7 | P43166 | 1/20 | 0.35 |
| ▸ | CA9 | Q16790 | 1/20 | 0.35 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.35 |
| ▸ | POLB | P06746 | 2/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
| ▸ | GLA | P06280 | 1/20 | 0.34 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.34 |
| ▸ | TSHR | P16473 | 3/20 | 0.33 |
| ▸ | TP53 | P04637 | 2/20 | 0.33 |
| ▸ | TRPA1 | O75762 | 2/20 | 0.32 |
| ▸ | LMNA | P02545 | 2/20 | 0.32 |
| ▸ | AGTR1 | P30556 | 1/20 | 0.32 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL37986 | 0.88 | CA4 (0.41) | ESR1ESR2CA1CA2CA4 | |
| Water SCHEMBL18606224 | 0.85 | POLB (0.39) | ESR1ESR2CA1CA2CA4 | |
| Ammonia Solution, Strong SCHEMBL2330946 | 0.85 | POLB (0.39) | ESR1ESR2CA1CA2CA4 | |
| SCHEMBL1974068 | 0.85 | CA1 (0.41) | ESR1ESR2CA1CA2CA4 | |
| Alcohol SCHEMBL28795240 | 0.85 | TAAR1 (0.31) | MGAM | |
| Methylamine SCHEMBL28410618 | 0.83 | POLB (0.38) | ESR1ESR2CA1CA2CA4 | |
| SCHEMBL2201675 | 0.83 | MGAM (0.33) | ESR1ESR2MGAMCA4POLB | |
| SCHEMBL2874122 | 0.83 | TSHR (0.33) | CA4POLBSMN1; SMN2TSHRTP53 | |
| SCHEMBL20592338 | 0.82 | POLB (0.39) | ESR1ESR2CA4POLBSMN1; SMN2 | |
| Dimethylamine SCHEMBL2870395 | 0.81 | POLB (0.37) | ESR1ESR2CA1CA2CA4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-118126540-A | Preparation method of modified titanium dioxide, preparation method of plastic and plastic | 成都先进金属材料产业技术研究院股份有限公司 | 2024-06-04 | — | — | CN | disclosed |
| CN-114106792-B | Modified lignin filtrate reducer and preparation method thereof | 中国石油化工股份有限公司 | 2023-01-20 | — | — | CN | disclosed |
| CN-114106792-A | Modified lignin filtrate reducer and preparation method thereof | 中国石油化工股份有限公司 | 2022-03-01 | — | — | CN | disclosed |
| CN-110280314-B | Method for improving water resistance and dust resistance of manganese-based low-temperature SCR catalyst | 中国科学院兰州化学物理研究所 | 2021-07-23 | — | — | CN | disclosed |
| EP-1757566-B1 | INTERLAYER FILM FOR GLASS LAMINATE AND GLASS LAMINATE | SEKISUI CHEMICAL CO LTD (JP) | 2012-09-12 | — | — | EP | disclosed |
| US-20090297832-A1 | INTERLAYER FILM FOR GLASS LAMINATE AND GLASS LAMINATE | SEKISUI CHEMICAL CO., LTD. | 2009-12-03 | — | — | US | disclosed |
| US-20070224340-A1 | Interlayer Film for Glass Laminate and Glass Laminate | SEKISHI CHEMICAL CO., LTD (JP) | 2007-09-27 | — | — | US | disclosed |
| EP-1757566-A1 | INTERLAYER FILM FOR GLASS LAMINATE AND GLASS LAMINATE | SEKISUI CHEMICAL CO., LTD. (JP) | 2007-02-28 | — | — | EP | disclosed |