⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL54111 | 1.00 | — | — | |
| SCHEMBL76382 | 1.00 | — | — | |
| SCHEMBL27668114 | 0.98 | MGAM (0.50) | — | |
| SCHEMBL27522306 | 0.98 | — | — | |
| SCHEMBL5866612 | 0.95 | MGAM (0.48) | — | |
| Formaldehyde SCHEMBL5845336 | 0.95 | MGAM (0.48) | — | |
| Ammonia Solution, Strong SCHEMBL27632918 | 0.95 | MGAM (0.48) | — | |
| SCHEMBL23093673 | 0.91 | MGAM (0.44) | — | |
| Lactic Acid SCHEMBL29124782 | 0.91 | TP53 (0.46) | — | |
| SCHEMBL15285367 | 0.91 | MGAM (0.44) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 254 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20260098281-A1 | METHODS FOR PRODUCING HIGHLY PURIFIED (R)-3’-HYDROXYBUTYL (R)-3’-HYDROXYBUTYRATE AND USE FOR ENHANCING BODILY FUNCTION AND TREATING DISEASE STATES | Romeo Tango, LLC (US) | 2026-04-09 | — | — | US | claimed |
| CN-119954638-A | Betaine R-3-hydroxybutyrate granule | 上海康鑫化工有限公司 | 2025-05-09 | — | — | CN | claimed |
| CN-119751253-A | Continuous flow synthesis method of ketoester | 苏州满元生物科技有限公司 | 2025-04-04 | — | — | CN | claimed |
| CN-114277068-B | Microbial fermentation preparation method of R-3-ethyl hydroxybutyrate | 珠海麦得发生物科技股份有限公司 | 2024-03-12 | — | — | CN | claimed |
| EP-4240345-A1 | LACTATE/KETONE BODY ESTERS | Aarhus Universitet (DK) | 2023-09-13 | — | — | EP | claimed |
| CN-116528848-A | Lactic acid/ketone body esters | 奥胡斯大学 | 2023-08-01 | — | — | CN | claimed |
| CN-116396163-A | Method for one-step catalytic synthesis of (R) -3-hydroxybutyric acid oligomer by using solid acid catalyst | 东莞理工学院 | 2023-07-07 | — | — | CN | claimed |
| US-20230174454-A1 | PROCESS OF SYNTHESIZING AND PURIFYING (3R)-HYDROXYBUTYL (3R)-HYDROXYBUTANOATE | GENOMATICA, INC. | 2023-06-08 | — | — | US | claimed |
| CN-116041177-A | Method for preparing R-3-hydroxybutyrate by degrading poly-3-hydroxybutyrate by recycling alcohol-trifluoroacetic acid solvent system | 东莞理工学院 | 2023-05-02 | — | — | CN | claimed |
| EP-4149918-A1 | PROCESS OF SYNTHESIZING AND PURIFYING (3R)-HYDROXYBUTYL (3R)-HYDROXYBUTANOATE | Genomatica, Inc. (US) | 2023-03-22 | — | — | EP | claimed |
| CN-114277068-A | Microbial fermentation preparation method of ethyl R-3-hydroxybutyrate | 珠海麦得发生物科技股份有限公司 | 2022-04-05 | — | — | CN | claimed |
| CN-111705068-B | Asymmetric synthesis method of ketoreductase with stereoselectivity and (R) -3-hydroxy ethyl butyrate | 宁波酶赛生物工程有限公司 | 2021-06-11 | — | — | CN | claimed |
| CN-112359071-A | Water-soluble controllable antibacterial substance and synthesis process thereof | 浙江英玛特生物科技有限公司 | 2021-02-12 | — | — | CN | claimed |
| CN-109852593-B | Recombinant ketoreductase and application thereof in preparation of R-3-hydroxybutyric acid and salts thereof | 洛阳华荣生物技术有限公司 | 2020-10-20 | — | — | CN | claimed |
| CN-111705068-A | Asymmetric synthesis method of ketoreductase with stereoselectivity and (R) -3-hydroxy ethyl butyrate | 宁波酶赛生物工程有限公司 | 2020-09-25 | — | — | CN | claimed |
| CN-108103044-B | Esterase WDEst17, and coding gene and application thereof | 中国科学院南海海洋研究所 | 2020-06-30 | — | — | CN | claimed |
| US-20120041225-A1 | KIT FOR AUTOMATED RESOLVING AGENT SELECTION AND METHOD THEREOF | VAIDYA NITEEN A (US) | 2012-02-16 | — | — | US | claimed |
| EP-1981831-A2 | KIT FOR AUTOMATED RESOLVING AGENT SELECTION AND METHOD THEREOF | Vaidya, Niteen A. (US) | 2008-10-22 | — | — | EP | claimed |
| WO-2007092264-A2 | KIT FOR AUTOMATED RESOLVING AGENT SELECTION AND METHOD THEREOF | VAIDYA NITEEN A (US) | 2007-08-16 | — | — | WO | claimed |
| US-20070185346-A1 | Kit for automated resolving agent selection and method thereof | VAIDYA NITEEN A | 2007-08-09 | — | — | US | claimed |