Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARA | Q07869 | 8/20 | 0.49 |
| ▸ | PPARG | P37231 | 6/20 | 0.44 |
| ▸ | PPARD | Q03181 | 2/20 | 0.44 |
| ▸ | MRGPRX4 | Q96LA9 | 2/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4327644 | 0.90 | PPARA (0.51) | PPARAPPARGPPARDMRGPRX4MEN1 | |
| SCHEMBL4327650 | 0.90 | PPARA (0.51) | PPARAPPARGPPARDMRGPRX4MEN1 | |
| SCHEMBL4327910 | 0.90 | PPARA (0.51) | PPARAPPARGPPARDMRGPRX4MEN1 | |
| SCHEMBL4332539 | 0.90 | PPARA (0.50) | PPARAPPARGPPARDMRGPRX4MEN1 | |
| SCHEMBL4339171 | 0.90 | PPARA (0.50) | PPARAPPARGPPARDMRGPRX4MEN1 | |
| SCHEMBL4332536 | 0.90 | PPARA (0.50) | PPARAPPARGPPARDMRGPRX4MEN1 | |
| SCHEMBL6653525 | 0.87 | PPARA (0.44) | PPARAPPARGPPARD | |
| SCHEMBL4336847 | 0.87 | PPARA (0.54) | PPARAPPARGPPARDMRGPRX4 | |
| SCHEMBL4341219 | 0.86 | PPARA (0.53) | PPARAPPARGPPARDMRGPRX4 | |
| SCHEMBL4334118 | 0.83 | MEN1 (0.54) | PPARAPPARGPPARDMRGPRX4MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7544835-B2 | Carboxylic acid derivative and salt thereof | EISAI R&D MANAGEMENT CO., LTD. (JP) | 2009-06-09 | — | — | US | disclosed |
| US-7544835-B2 | Carboxylic acid derivative and salt thereof | EISAI R&D MANAGEMENT CO., LTD. (JP) | 2009-06-09 | — | — | US | disclosed |
| US-7544835-B2 | Carboxylic acid derivative and salt thereof | EISAI R&D MANAGEMENT CO., LTD. (JP) | 2009-06-09 | — | — | US | disclosed |