Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MTOR | P42345 | 2/20 | 0.38 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.38 |
| ▸ | LSS | P48449 | 1/20 | 0.38 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.38 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.38 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.38 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.38 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.38 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | PLA2G1B | P04054 | 1/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.36 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4351483 | 0.86 | MTOR (0.42) | MTORHDAC1LSSHDAC3HDAC2 | |
| SCHEMBL4347804 | 0.81 | KCNH2 (0.39) | MTORHDAC1LSSHDAC3HDAC2 | |
| SCHEMBL4359745 | 0.81 | TMPRSS4 (0.50) | MTORHDAC1LSSHDAC3HDAC2 | |
| SCHEMBL4355927 | 0.77 | LSS (0.44) | MTORHDAC1LSSHDAC3HDAC2 | |
| SCHEMBL4347497 | 0.76 | MAPT (0.47) | MTORHDAC1LSSHDAC3HDAC2 | |
| SCHEMBL4357500 | 0.76 | HDAC3 (0.46) | MTORHDAC1LSSHDAC3HDAC2 | |
| SCHEMBL4345512 | 0.76 | KMT2A (0.49) | MAPTMEN1GAAKMT2AALDH1A1 | |
| SCHEMBL4354458 | 0.75 | MTOR (0.42) | MTORHDAC1LSSHDAC3HDAC2 | |
| SCHEMBL4354240 | 0.75 | MTOR (0.43) | MTORHDAC1LSSHDAC3HDAC2 | |
| SCHEMBL4348897 | 0.74 | MTOR (0.50) | MTORHDAC1LSSHDAC3HDAC2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2100876-A2 | New compounds for the inhibition of rotamases and use thereof | Jerini AG (DE) | 2009-09-16 | — | — | EP | claimed |