SCHEMBL43458

SCHEMBL43458

[NH]C(=O)O

nearest known ligand 0.00

⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL168109 0.77
SCHEMBL3760424 0.76
SCHEMBL5518651 0.72
Bicarbonate SCHEMBL19897289 0.71
SCHEMBL689736 0.71
SCHEMBL1414101 0.71
SCHEMBL992286 0.71
Bicarbonate SCHEMBL1179 0.68
Bicarbonate SCHEMBL15271537 0.68
Bicarbonate SCHEMBL11066368 0.68 CA1 (1.00)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Appears in 7021 patents — a generic fragment claimed broadly, so it's down-weighted as IP noise. Top by claim status then date:

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20240228469-A1 PCSK9 INHIBITORS AND METHODS OF USE THEREOF ASTRAZENECA AB (SE) 2024-07-11 US claimed
US-20240217951-A1 PCSK9 INHIBITORS AND METHODS OF USE THEREOF ASTRAZENECA AB (SE) 2024-07-04 US claimed
US-20240207413-A1 PROTEOLYSIS-TARGETING CHIMERIC MOLECULES (PROTACS) THAT INDUCE DEGRADATION OF C-MYC PROTEIN NORTHWESTERN UNIVERSITY 2024-06-27 US claimed
CN-112002809-B Photoelectric conversion element and solid-state imaging device 索尼半导体解决方案公司 2024-06-18 CN claimed
CN-112002807-B Photoelectric conversion element, solid-state imaging device, and electronic apparatus 索尼半导体解决方案公司 2024-06-18 CN claimed
CN-118010981-A Nucleic acid-assisted fluorescent coding microsphere and preparation method and application thereof 湖南大学 2024-05-10 CN claimed
EP-3939976-B1 PRODRUG OF CASPASE INHIBITOR LG CHEMICAL LTD (KR) 2024-05-01 EP claimed
EP-4347575-A1 BENZOTHIA(DI)AZEPINE COMPOUNDS AND THEIR USE AS BILE ACID MODULATORS Albireo AB (SE) 2024-04-10 EP claimed
WO-2024062089-A1 PCSK9 INHIBITORS AND METHODS OF USE THEREOF ASTRAZENECA AB (SE) 2024-03-28 WO claimed
WO-2024062090-A1 PCSK9 INHIBITORS AND METHODS OF USE THEREOF ASTRAZENECA AB (SE) 2024-03-28 WO claimed
US-4308380-A 2-Lower alkyl-2 or 3-cephem-4-carboxylic acid derivatives FUJISAWA PHARMACEUTICAL CO., LTD. (JP) 1981-12-29 US claimed
US-4272435-A Process for the preparation of azo compounds from amino compounds in the presence of a phase transfer catalyst SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 1981-06-09 US claimed
US-4268624-A Photographic light-sensitive sheet for the color diffusion transfer process FUJI PHOTO FILM CO., LTD. (JP) 1981-05-19 US claimed
US-4255509-A NAPHTHYL-AZO-PHENYL COMPOUND FUJI PHOTO FILM CO., LTD. (JP) 1981-03-10 US claimed
US-4250246-A MAGENTA DYE-RELEASING REDOX COMPOUND; COLORFASTNESS FUJI PHOTO FILM CO., LTD. (JP) 1981-02-10 US claimed
US-4233425-A CURABLE FLOORING MATERIALS THE DOW CHEMICAL COMPANY (US) 1980-11-11 US claimed
EP-0000890-B1 RADIATION CURABLE URETHANE-ACRYLATE BINDERS BAYER AG (DE) 1980-10-01 EP claimed
US-4225695-A LACQUERS FOR LEATHER BAYER AKTIENGESELLSCHAFT (DE) 1980-09-30 US claimed
EP-0000890-A2 Radiation curable urethane-acrylate binders BAYER AG (DE) 1979-03-07 EP claimed
US-4083847-A Transiently water-soluble disperse mono-azo dyes containing a diamino-methylene-carbacyl group CIBA-GEIGY CORPORATION (US) 1978-04-11 US claimed