Known targets — ChEMBL curated mechanism
CACNA1CCACNA1DCACNA1FCACNA1SDPP4HTR1BHTR1D
The experimentally established mechanism targets of Benzoic Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 4/20 | 0.88 |
| ▸ | DAO | P14920 | 1/20 | 0.88 |
| ▸ | NAPRT | Q6XQN6 | 1/20 | 0.88 |
| ▸ | CES2 | O00748 | 3/20 | 0.70 |
| ▸ | CES1 | P23141 | 3/20 | 0.70 |
| ▸ | SRD5A2 | P31213 | 2/20 | 0.70 |
| ▸ | TP53 | P04637 | 1/20 | 0.65 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.58 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.54 |
| ▸ | CA12 | O43570 | 2/20 | 0.52 |
| ▸ | CA1 | P00915 | 2/20 | 0.52 |
| ▸ | CA2 | P00918 | 2/20 | 0.52 |
| ▸ | CA3 | P07451 | 2/20 | 0.52 |
| ▸ | CA4 | P22748 | 2/20 | 0.52 |
| ▸ | CA6 | P23280 | 2/20 | 0.52 |
| ▸ | CA5A | P35218 | 2/20 | 0.52 |
| ▸ | CA7 | P43166 | 2/20 | 0.52 |
| ▸ | CA9 | Q16790 | 2/20 | 0.52 |
| ▸ | CA14 | Q9ULX7 | 2/20 | 0.52 |
| ▸ | CA5B | Q9Y2D0 | 2/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Benzoic Acid SCHEMBL20574965 | 1.00 | TSHR (0.88) | TSHRDAONAPRTCES2CES1 | |
| Benzoic Acid SCHEMBL10490725 | 1.00 | TSHR (0.88) | TSHRDAONAPRTCES2CES1 | |
| Benzoic Acid SCHEMBL28791118 | 1.00 | TSHR (0.88) | TSHRDAONAPRTCES2CES1 | |
| Benzoic Acid SCHEMBL29182064 | 1.00 | TSHR (0.88) | TSHRDAONAPRTCES2CES1 | |
| Benzoic Acid SCHEMBL28917082 | 1.00 | TSHR (0.88) | TSHRDAONAPRTCES2CES1 | |
| Benzoic Acid SCHEMBL1522973 | 1.00 | TSHR (0.88) | TSHRDAONAPRTCES2CES1 | |
| Benzoic Acid SCHEMBL21145091 | 0.97 | TSHR (0.82) | TSHRDAONAPRTCES2CES1 | |
| Benzoic Acid SCHEMBL27764374 | 0.94 | TSHR (0.88) | TSHRDAONAPRTCES2CES1 | |
| Benzoic Acid SCHEMBL1615025 | 0.94 | TSHR (0.88) | TSHRDAONAPRTCES2CES1 | |
| Benzoic Acid SCHEMBL7719037 | 0.94 | TSHR (1.00) | TSHRDAONAPRTCES2CES1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 40 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-119505185-A | PAF supported ruthenium catalyst and preparation method and application thereof | 南昌大学 | 2025-02-25 | — | — | CN | claimed |
| CN-112625157-B | Catalyst for preparing ultra-pure polypropylene and preparation method for preparing ultra-pure polypropylene by batch bulk method | 黄河三角洲京博化工研究院有限公司 | 2023-04-28 | — | — | CN | claimed |
| CN-113897186-B | Oil-based gel consolidation plugging system for oil-based drilling fluid applicable to malignant leakage stratum and preparation method of oil-based gel consolidation plugging system | 中国石油大学(华东) | 2022-11-25 | — | — | CN | claimed |
| CN-113897186-A | Oil-based gel consolidation plugging system for oil-based drilling fluid applicable to malignant leakage stratum and preparation method of oil-based gel consolidation plugging system | 中国石油大学(华东) | 2022-01-07 | — | — | CN | claimed |
| CN-108606360-B | Application of diester-type tobacco flavor in cigarettes | 河南中烟工业有限责任公司 | 2021-05-18 | — | — | CN | claimed |
| CN-112625157-A | Catalyst for preparing ultrapure polypropylene and preparation method for preparing ultrapure polypropylene by batch bulk method | 黄河三角洲京博化工研究院有限公司 | 2021-04-09 | — | — | CN | claimed |
| US-4560722-A | BORIC ACID, CATALYST | GENERAL ELECTRIC COMPANY (US) | 1985-12-24 | — | — | US | claimed |
| CN-119546184-A | Novel agrochemical formulations | 巴斯夫欧洲公司 | 2025-02-28 | — | — | CN | disclosed |
| CN-119505185-A | PAF supported ruthenium catalyst and preparation method and application thereof | 南昌大学 | 2025-02-25 | — | — | CN | disclosed |
| CN-118043941-A | Methods and formulations for sacrificial support, surface protection and waiting time management using stimulus-responsive polymers | 朗姆研究公司 | 2024-05-14 | — | — | CN | disclosed |
| CN-113811287-B | Low VOC multi-functional additives for improving waterborne polymer film properties | 朗盛公司 | 2023-11-17 | — | — | CN | disclosed |
| CN-114127045-B | Method for producing diacyl peroxide | 诺力昂化学品国际有限公司 | 2023-10-13 | — | — | CN | disclosed |
| CN-113993844-B | Method for producing diacyl peroxide | 诺力昂化学品国际有限公司 | 2023-10-13 | — | — | CN | disclosed |
| EP-2078724-B1 | PROCESS FOR PRODUCTION OF DIALKYLTIN DIALKOXIDES | ASAHI CHEMICAL IND (JP) | 2016-11-30 | — | — | EP | disclosed |
| WO-2012010918-A2 | OPTICAL DEVICES | MEDICONTUR ORVOSTECHNIKAI KFT. (HU) | 2012-01-26 | — | — | WO | disclosed |
| US-8008518-B2 | Process for producing dialkyl tin dialkoxides | ASAHI KASEI CHEMICALS CORPORATION (JP) | 2011-08-30 | — | — | US | disclosed |
| US-20100041908-A1 | PROCESS FOR PRODUCING DIALKYL TIN DIALKOXIDES | ASAHI KASEI KABUSHIKI KAISHA (JP) | 2010-02-18 | — | — | US | disclosed |
| EP-2078724-A1 | PROCESS FOR PRODUCTION OF DIALKYLTIN DIALKOXIDES | Asahi Kasei Chemicals Corporation (JP) | 2009-07-15 | — | — | EP | disclosed |
| US-4560722-A | BORIC ACID, CATALYST | GENERAL ELECTRIC COMPANY (US) | 1985-12-24 | — | — | US | disclosed |
| US-4415747-A | Process for making ethylene glycol derivatives | UNION CARBIDE CORPORATION (US) | 1983-11-15 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100041908-A1 | PROCESS FOR PRODUCING DIALKYL TIN DIALKOXIDES | DEK, DDT, DERA | TSHR 2537/4885DAO 5/4885NAPRT 378/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.