SCHEMBL4346880

SCHEMBL4346880

CSC(=O)NN

nearest known ligand 0.00

⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Methylsulfanylmethane SCHEMBL27750764 0.73
SCHEMBL2307861 0.72 CYP1A2 (0.44)
SCHEMBL9577385 0.72
SCHEMBL15761278 0.69
SCHEMBL22652612 0.69
SCHEMBL3434601 0.69
SCHEMBL11186861 0.69
SCHEMBL7812300 0.69
SCHEMBL2085562 0.67
SCHEMBL11718113 0.67

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 25 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-115259969-B Biological fermentation organic fertilizer and preparation method thereof 北京泰丰平生物科技有限公司 2023-10-10 CN disclosed
US-8552031-B2 3-ethylidenehydrazino substituted heterocyclic compounds as thrombopoietin receptor activators NISSAN CHEMICAL INDUSTRIES, LTD. (JP) 2013-10-08 US disclosed
US-20090281317-A1 3-ETHYLIDENEHYDRAZINO SUBSTITUTED HETEROCYCLIC COMPOUNDS AS THROMBOPOIETIN RECEPTOR ACTIVATORS NISSAN CHEMICAL INDUSTRIES LTD. (JP) 2009-11-12 US disclosed
EP-1819692-A1 3-ETHYLIDENEHYDRAZINO SUBSTITUTED HETEROCYCLIC COMPOUNDS AS THROMBOPOIETIN RECEPTOR ACTIVATORS Nissan Chemical Industries, Ltd. (JP) 2007-08-22 EP disclosed
WO-2006062240-A1 3-ETHYLIDENEHYDRAZINO SUBSTITUTED HETEROCYCLIC COMPOUNDS AS THROMBOPOIETIN RECEPTOR ACTIVATORS NISSAN CHEMICAL INDUSTRIES, LTD. (JP) 2006-06-15 WO disclosed
US-5753642-A AGRICULTURE, MEDICINE ROHM AND HAAS COMPANY (US) 1998-05-19 US disclosed
US-5728715-A FOR MAMMALS, AGRICULTURE, RICE, WHEAT, TOMATOES ROHM AND HAAS COMPANY (US) 1998-03-17 US disclosed
US-5728698-A AGRICULTURAL USE, RICE, WHEAT ROHM AND HAAS COMPANY (US) 1998-03-17 US disclosed
US-5728694-A Dihydropyridazinones, pyridazinones and related compounds as fungicides ROHM AND HAAS COMPANY (US) 1998-03-17 US disclosed
US-5726176-A FOR CONTROLLING AGRICULTURAL AND MAMMALIAN FUNGAL DISEASES ROHM AND HAAS COMPANY (US) 1998-03-10 US disclosed
EP-0085227-B1 THIADIAZINE DERIVATIVES, AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM IMPERIAL CHEMICAL INDUSTRIES PLC (GB) 1991-04-03 EP disclosed
US-4980479-A Reacting an acyc cyanide with carboxylic acid anhydride BAYER AKTIENGESELLSCHAFT (DE) 1990-12-25 US disclosed
EP-0381374-A1 Phosphodiesterase inhibitors LES LABORATOIRES BEECHAM S.A. (FR) 1990-08-08 EP disclosed
US-4870077-A INOTROPIC, HKYPOTENSIVE, CARDIOTONIC BOEHRINGER MANNHEIM GMBH (DE) 1989-09-26 US disclosed
US-4788194-A CARDIOTONIC AGENTS, HYPOTENSIVE AGENTS IMPERIAL CHEMICAL INDUSTRIES PLC (GB) 1988-11-29 US disclosed
US-4716164-A CARDIOTONIC, HYPOTENSIVE IMPERIAL CHEMICAL INDUSTRIES PLC (GB) 1987-12-29 US disclosed
US-4594427-A Preparation of novel 5-acyloxy-4-(5H)-oxazolonium salts suited for use as intermediates for triazinone herbicides BAYER AKTIENGESELLSCHAFT (DE) 1986-06-10 US disclosed
US-4558045-A CARDIOTONIC AND HYPOTENSIVE ACTIVITY IMPERIAL CHEMICAL INDUSTRIES, PLC (GB) 1985-12-10 US disclosed
US-4489073-A HYPOTENSIVE AND CARDIOTONIC AGENTS IMPERIAL CHEMICAL INDUSTRIES, PLC (GB) 1984-12-18 US disclosed
EP-0085227-A1 Thiadiazine derivatives, and pharmaceutical compositions containing them IMPERIAL CHEMICAL INDUSTRIES PLC (GB) 1983-08-10 EP disclosed