SCHEMBL434792

SCHEMBL434792

Nc1ccc(CCCC(=O)O)cc1

nearest known ligand 0.67

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
SMN1; SMN2 Q16637 2/20 0.67
HDAC3 O15379 1/20 0.67
MAPK1 P28482 1/20 0.67
ADRA1A P35348 1/20 0.67
HDAC4 P56524 1/20 0.67
SLC6A3 Q01959 1/20 0.67
HDAC1 Q13547 1/20 0.67
HDAC7 Q8WUI4 1/20 0.67
HDAC2 Q92769 1/20 0.67
HDAC10 Q969S8 1/20 0.67
HDAC11 Q96DB2 1/20 0.67
HDAC8 Q9BY41 1/20 0.67
HDAC6 Q9UBN7 1/20 0.67
HDAC9 Q9UKV0 1/20 0.67
HDAC5 Q9UQL6 1/20 0.67
HSD17B10 Q99714 1/20 0.61
FFAR1 O14842 3/20 0.58
MAOB P27338 4/20 0.57
MAPT P10636 2/20 0.57
RXFP1 Q9HBX9 1/20 0.57

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11760587 0.94 SMN1; SMN2 (0.60) SMN1; SMN2HDAC3MAPK1ADRA1AHDAC4
SCHEMBL224789 0.94 MAPT (0.66) SMN1; SMN2HDAC3MAPK1ADRA1AHDAC4
SCHEMBL10987845 0.92 MAPT (0.69) SMN1; SMN2HDAC3MAPK1ADRA1AHDAC4
SCHEMBL4423281 0.92 MAPT (0.69) SMN1; SMN2HDAC3MAPK1ADRA1AHDAC4
SCHEMBL28105634 0.89 SMN1; SMN2 (0.55) SMN1; SMN2HDAC3MAPK1ADRA1AHDAC4
SCHEMBL6208836 0.89 SMN1; SMN2 (0.82) SMN1; SMN2HDAC3MAPK1ADRA1AHDAC4
SCHEMBL11036075 0.88 SMN1; SMN2 (0.67) SMN1; SMN2HDAC3MAPK1ADRA1AHDAC4
SCHEMBL73828 0.87 FFAR1 (0.65) FFAR1MAOBGFERMAOAKEAP1
SCHEMBL69789 0.87 SMN1; SMN2 (0.78) SMN1; SMN2HDAC3MAPK1ADRA1AHDAC4
Hydrochloric Acid SCHEMBL10867576 0.86 SMN1; SMN2 (0.64) SMN1; SMN2HDAC3MAPK1ADRA1AHDAC4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1276 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2025151884-A1 USE OF GLYCOSAMINOGLYCAN SULFATED POLYSACCHARIDES SUCH AS SODIUM PENTOSAN POLYSULFATE IN COMBINATION WITH PERMEATION AGENTS TO TREAT ALZHEIMER'S DISEASE PARSONS C LOWELL (US) 2025-07-17 WO claimed
EP-3274322-B1 STABLE COMPOSITIONS FOR PREVENTION / PROPHYLACTIC TREATMENT OF POISON IVY DERMATITIS THE UNIV OF MISSISSIPPI (US) 2024-08-14 EP claimed
US-20240238317-A1 METHODS FOR REDUCING INTRAOCULAR PRESSURE UNIV MISSISSIPPI (US) 2024-07-18 US claimed
CN-118103073-A Method for reducing intraocular pressure 密西西比大学 2024-05-28 CN claimed
CN-118056598-A Preparation method of pervaporation membrane, application of pervaporation membrane in hydrogen chloride gas refining and refining method of pervaporation membrane 万华化学集团股份有限公司 2024-05-21 CN claimed
EP-4337319-A1 METHODS FOR REDUCING INTRAOCULAR PRESSURE University of Mississippi (US) 2024-03-20 EP claimed
EP-4267118-A1 XANTHOPHYLL DERIVATIVES Axelyf ehf. (IS) 2023-11-01 EP claimed
WO-2022241456-A1 METHODS FOR REDUCING INTRAOCULAR PRESSURE UNIVERSITY OF MISSISSIPPI (US) 2022-11-17 WO claimed
WO-2022140580-A1 XANTHOPHYLL DERIVATIVES ALMARSSON ORN (US) 2022-06-30 WO claimed
EP-3059004-B1 METHOD FOR REMOVING SOX FROM GAS WITH COMPLEX ALCOHOL-AMINE SOLUTION BEIJING BOYUAN HENGSHENG HIGH TECH CO LTD (CN) 2021-06-30 EP claimed
EP-0758843-A4 MODIFIED AMINO ACIDS FOR DRUG DELIVERY EMISPHERE TECH INC (US) 1998-05-20 EP claimed
WO-1998001136-A9 FORMULATIONS OF VESICANT DRUGS AND METHODS OF USE THEREOF 1998-04-23 WO claimed
WO-1998001136-A1 FORMULATIONS OF VESICANT DRUGS AND METHODS OF USE THEREOF BAYLOR COLLEGE OF MEDICINE (US) 1998-01-15 WO claimed
US-5629020-A Modified amino acids for drug delivery EMISPHERE TECHNOLOGIES, INC. (US) 1997-05-13 US claimed
EP-0758843-A1 MODIFIED AMINO ACIDS FOR DRUG DELIVERY Emisphere Technologies, Inc. (US) 1997-02-26 EP claimed
EP-0696208-A4 ORAL DRUG DELIVERY COMPOSITIONS AND METHODS EMISPHERE TECH INC (US) 1997-01-29 EP claimed
WO-1996009813-A9 DIKETOPIPERAZINE-BASED DELIVERY SYSTEMS 1996-09-26 WO claimed
EP-0696208-A1 ORAL DRUG DELIVERY COMPOSITIONS AND METHODS Emisphere Technologies, Inc. (US) 1996-02-14 EP claimed
WO-1995028838-A1 MODIFIED AMINO ACIDS FOR DRUG DELIVERY EMISPHERE TECHNOLOGIES, INC. (US) 1995-11-02 WO claimed
WO-1994023767-A1 ORAL DRUG DELIVERY COMPOSITIONS AND METHODS EMISPHERE TECHNOLOGIES, INC. (US) 1994-10-27 WO claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20240238317-A1 METHODS FOR REDUCING INTRAOCULAR PRESSURE CIT, ROCK1, RHOA SMN1; SMN2 4857/4885HDAC3 3077/4885MAPK1 324/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.