SCHEMBL434846

SCHEMBL434846

c1nc(N2CCNCC2)nc(N2CCOCC2)n1

nearest known ligand 0.55

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
POLB P06746 1/20 0.55
PIK3CA P42336 5/20 0.51
PIK3CD O00329 2/20 0.51
PIK3CB P42338 2/20 0.51
PIK3R1 P27986 2/20 0.51
PIK3CG P48736 1/20 0.51
HRH1 P35367 1/20 0.50
SMN1; SMN2 Q16637 2/20 0.48
USP2 O75604 1/20 0.48
TDP1 Q9NUW8 1/20 0.48
KDM4E B2RXH2 2/20 0.47
ALDH1A1 P00352 2/20 0.47
MTOR P42345 1/20 0.44
ADRB1 P08588 1/20 0.44
MAPK1 P28482 2/20 0.44
TSHR P16473 1/20 0.43
KMT2A Q03164 1/20 0.43
NPSR1 Q6W5P4 1/20 0.43
CASP1 P29466 1/20 0.43
CASP4 P49662 1/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL16238117 0.89 PIK3CA (0.56) POLBPIK3CAPIK3CDPIK3CBPIK3R1
SCHEMBL28710773 0.89 HRH1 (0.61) POLBHRH1SMN1; SMN2USP2TDP1
SCHEMBL778143 0.87 HRH1 (0.65) POLBPIK3CAPIK3CDPIK3CBPIK3R1
SCHEMBL778162 0.87 HRH1 (0.65) POLBPIK3CAPIK3CDPIK3CBPIK3R1
SCHEMBL2524177 0.83 MAPK1 (0.58) PIK3CAPIK3CDPIK3CBPIK3R1PIK3CG
SCHEMBL4316997 0.81 TSHR (0.59) PIK3CAPIK3CDPIK3CBPIK3R1SMN1; SMN2
SCHEMBL2523906 0.81 MAPK1 (0.53) PIK3CAPIK3CDPIK3CBPIK3R1PIK3CG
SCHEMBL4462897 0.80 CYP2C19 (0.58) PIK3CBSMN1; SMN2ALDH1A1ADRB1CASP1
SCHEMBL778170 0.79 HRH1 (0.55) POLBPIK3CAPIK3CDPIK3CBPIK3R1
SCHEMBL777894 0.79 HRH1 (0.55) POLBPIK3CAPIK3CDPIK3CBPIK3R1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 22 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2596055-B1 FLAME RETARDANT INSULATED ELECTRICAL WIRE DSM IP ASSETS BV (NL) 2014-08-20 EP claimed
US-20130206448-A1 FLAME RETARDANT INSULATED ELECTRICAL WIRE DSM IP ASSETS B.V. (NL) 2013-08-15 US claimed
EP-2596055-A1 FLAME RETARDANT INSULATED ELECTRICAL WIRE DSM IP Assets B.V. (NL) 2013-05-29 EP claimed
CN-103003344-A Flame-retardant insulated electrical conductor DSM IP ASSETS BV 2013-03-27 CN claimed
WO-2012010453-A1 FLAME RETARDANT INSULATED ELECTRICAL WIRE DSM IP ASSETS B.V. (NL) 2012-01-26 WO claimed
WO-2010018061-A1 WRAPPING TAPE MADE OF A TPU FOIL WITH COEXTRUDED RELEASE TESA SE (DE) 2010-02-18 WO claimed
WO-2008151893-A1 COMPOUND AND WRAPPING TAPE CONSISTING OF A TPU FILM TESA SE (DE) 2008-12-18 WO claimed
WO-2008151897-A1 WRAPPING TAPE HAVING A FILM MADE OF TPU TESA SE (DE) 2008-12-18 WO claimed
EP-4126810-A1 USE OF SUBSTITUTED CINNAMIC ACID ESTERS AS STABILISERS FOR ORGANIC MATERIALS, STABILISED ORGANIC MATERIAL, METHOD FOR STABILISING ORGANIC MATERIALS AND SPECIFIC CINAMIC ACID ESTERS Fraunhofer-Gesellschaft zur Förderung der angewandten Forschung e.V. (DE) 2023-02-08 EP disclosed
CN-115135742-A Flame retardant composition and flame retardant thermoplastic resin composition containing the same 大八化学工业株式会社 2022-09-30 CN disclosed
EP-4025629-A1 OLIGOMER OR POLYMER, COMPOSITION, USE OF THE OLIGOMER OR POLYMER AND INTERMEDIATE Fraunhofer-Gesellschaft zur Förderung der angewandten Forschung e.V. (DE) 2022-07-13 EP disclosed
WO-2021191078-A1 USE OF SUBSTITUTED CINNAMIC ACID ESTERS AS STABILISERS FOR ORGANIC MATERIALS, STABILISED ORGANIC MATERIAL, METHOD FOR STABILISING ORGANIC MATERIALS AND SPECIFIC CINAMIC ACID ESTERS Fraunhofer-Gesellschaft zur Förderung der angewandten Forschung e.V. (DE) 2021-09-30 WO disclosed
WO-2021043489-A1 OLIGOMER OR POLYMER, COMPOSITION, USE OF THE OLIGOMER OR POLYMER AND INTERMEDIATE Fraunhofer-Gesellschaft zur Förderung der angewandten Forschung e.V. (DE) 2021-03-11 WO disclosed
EP-3313938-B1 POLYMER COMPOSITION HAVING DELAYED CRYSTALLIZATION BEHAVIOR, ADDITIVE COMPOSITION THAT INFLUENCES THE CRYSTALLIZATION BEHAVIOR, METHOD FOR LOWERING THE CRYSTALLIZATION POINT, AND USE OF AN ADDITIVE COMPOSITION FRAUNHOFER GES FORSCHUNG (DE) 2019-08-07 EP disclosed
US-20130206448-A1 FLAME RETARDANT INSULATED ELECTRICAL WIRE DSM IP ASSETS B.V. (NL) 2013-08-15 US disclosed
EP-2596055-A1 FLAME RETARDANT INSULATED ELECTRICAL WIRE DSM IP Assets B.V. (NL) 2013-05-29 EP disclosed
CN-103003344-A Flame-retardant insulated electrical conductor DSM IP ASSETS BV 2013-03-27 CN disclosed
WO-2012010453-A1 FLAME RETARDANT INSULATED ELECTRICAL WIRE DSM IP ASSETS B.V. (NL) 2012-01-26 WO disclosed
CN-100376628-C Refractory polypropylene composite SHANGHAI RES INST OF SYNTHETIC (CN) 2008-03-26 CN disclosed
CN-1827678-A Refractory polypropylene composite SHANGHAI RES INST OF SYNTHETIC (CN) 2006-09-06 CN disclosed