Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARA | Q07869 | 15/20 | 0.51 |
| ▸ | PPARG | P37231 | 13/20 | 0.49 |
| ▸ | PPARD | Q03181 | 7/20 | 0.49 |
| ▸ | FFAR1 | O14842 | 2/20 | 0.43 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.42 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.42 |
| ▸ | MRGPRX4 | Q96LA9 | 1/20 | 0.42 |
| ▸ | SLC2A1 | P11166 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4335069 | 0.91 | PPARA (0.48) | PPARAPPARGPPARD | |
| SCHEMBL4334094 | 0.89 | PPARA (0.59) | PPARAPPARGPPARDCYP1A2 | |
| SCHEMBL4327910 | 0.89 | PPARA (0.51) | PPARAPPARGPPARDCYP1A2CYP2D6 | |
| SCHEMBL4327644 | 0.89 | PPARA (0.51) | PPARAPPARGPPARDCYP1A2CYP2D6 | |
| SCHEMBL4327650 | 0.89 | PPARA (0.51) | PPARAPPARGPPARDCYP1A2CYP2D6 | |
| SCHEMBL4332329 | 0.89 | PPARG (0.48) | PPARAPPARGPPARDCYP1A2 | |
| SCHEMBL4334556 | 0.87 | PPARA (0.46) | PPARAPPARGPPARDMRGPRX4 | |
| SCHEMBL4339633 | 0.85 | PPARG (0.55) | PPARAPPARGPPARDCYP1A2CYP2D6 | |
| SCHEMBL4339632 | 0.85 | PPARG (0.54) | PPARAPPARGPPARD | |
| SCHEMBL4337033 | 0.81 | PPARA (0.58) | PPARAPPARGPPARD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7544835-B2 | Carboxylic acid derivative and salt thereof | EISAI R&D MANAGEMENT CO., LTD. (JP) | 2009-06-09 | — | — | US | disclosed |
| US-7544835-B2 | Carboxylic acid derivative and salt thereof | EISAI R&D MANAGEMENT CO., LTD. (JP) | 2009-06-09 | — | — | US | disclosed |
| US-7544835-B2 | Carboxylic acid derivative and salt thereof | EISAI R&D MANAGEMENT CO., LTD. (JP) | 2009-06-09 | — | — | US | disclosed |
| EP-1380562-A1 | CARBOXYLIC ACID DERIVATIVE AND SALT THEREOF | Eisai Co., Ltd. (JP) | 2004-01-14 | — | — | EP | disclosed |