SCHEMBL4348629

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL4346455	0.89	KDM4E (0.52)	HTTKMT2AMEN1SMN1; SMN2KDM4E
	SCHEMBL4346610	0.88	KDM4E (0.55)	HTTKMT2AMEN1SMN1; SMN2KDM4E
	SCHEMBL4343366	0.84	KDM4E (0.48)	HTTKMT2AMEN1SMN1; SMN2KDM4E
	SCHEMBL4343132	0.83	MEN1 (0.63)	KMT2AMEN1SMN1; SMN2KDM4ETAAR1
	SCHEMBL4340557	0.83	MEN1 (0.63)	KMT2AMEN1SMN1; SMN2KDM4ETAAR1
	SCHEMBL4347718	0.83	MEN1 (0.63)	KMT2AMEN1SMN1; SMN2KDM4ETAAR1
	SCHEMBL4348017	0.80	MEN1 (0.57)	KMT2AMEN1SMN1; SMN2KDM4ETAAR1
	SCHEMBL4343262	0.80	MEN1 (0.57)	KMT2AMEN1SMN1; SMN2KDM4ETAAR1
	SCHEMBL5963825	0.80	CNR2 (0.61)	HTTKMT2AMEN1SMN1; SMN2KDM4E
	SCHEMBL5964627	0.77	MEN1 (0.50)	HTTKMT2AMEN1SMN1; SMN2KDM4E

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.