SCHEMBL4348730

SCHEMBL4348730

O=C(Oc1ccccc1)c1ccc(C(=O)c2ccc(C(=O)Oc3ccccc3)cc2)cc1

nearest known ligand 0.63

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
PARP10 Q53GL7 1/20 0.63
ELANE P08246 6/20 0.62
PRSS1 P07477 1/20 0.61
ACR P10323 1/20 0.61
TMPRSS15 P98073 1/20 0.61
NSD2 O96028 1/20 0.58
MAPT P10636 5/20 0.57
SMN1; SMN2 Q16637 1/20 0.57
SRD5A2 P31213 1/20 0.57
KMT2A Q03164 4/20 0.56
MEN1 O00255 3/20 0.56
ALDH1A1 P00352 4/20 0.55
TDP1 Q9NUW8 2/20 0.55
L3MBTL1 Q9Y468 1/20 0.55
PKM P14618 1/20 0.55

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8206009 0.94 PARP10 (0.72) PARP10ELANEMAPTKMT2AMEN1
SCHEMBL70034 0.93 PARP10 (0.70) PARP10PRSS1ACRTMPRSS15NSD2
SCHEMBL13019492 0.92 PARP10 (0.61) PARP10ELANEPRSS1ACRTMPRSS15
SCHEMBL13019495 0.92 PARP10 (0.61) PARP10ELANEPRSS1ACRTMPRSS15
SCHEMBL6662159 0.89 PARP10 (0.67) PARP10ELANEPRSS1ACRTMPRSS15
SCHEMBL10524082 0.89 TDP1 (0.62) PARP10ELANEPRSS1ACRTMPRSS15
SCHEMBL8205435 0.89 PARP10 (0.78) PARP10ELANEPRSS1ACRTMPRSS15
SCHEMBL31888 0.89 PARP10 (0.70) PARP10PRSS1ACRTMPRSS15NSD2
SCHEMBL1870544 0.89 PARP10 (0.70) PARP10PRSS1ACRTMPRSS15NSD2
SCHEMBL10783081 0.88 PARP10 (0.66) PARP10ELANEMAPTKMT2AMEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1457511-B1 CROSSLINKABLE AROMATIC RESINS HAVING PROTONIC ACID GROUPS AND ION CONDUCTIVE POLYMER MEMBRANES BINDERS AND FUEL CELLS MADE BY USING THE SAME MITSUI CHEMICALS INC (JP) 2009-07-15 EP disclosed
US-7345135-B2 Crosslinkable aromatic resin having protonic acid group, and ion conductive polymer membrane, binder and fuel cell using the resin MITSUI CHEMICALS, INC. (JP) 2008-03-18 US disclosed
US-20040191602-A1 Crosslinkable aromatic resin having protonic acid group, and ion conductive polymer membrane, binder and fuel cell using the resin MITSUI CHEMICALS, INC. (JP) 2004-09-30 US disclosed
EP-1457511-A1 CROSSLINKABLE AROMATIC RESINS HAVING PROTONIC ACID GROUPS AND ION CONDUCTIVE POLYMER MEMBRANES BINDERS AND FUEL CELLS MADE BY USING THE SAME Mitsui Chemicals, Inc. (JP) 2004-09-15 EP disclosed