Known targets — ChEMBL curated mechanism
The experimentally established mechanism targets of Terephthalic Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 2/20 | 0.70 |
| ▸ | CA1 | P00915 | 4/20 | 0.67 |
| ▸ | CA2 | P00918 | 4/20 | 0.67 |
| ▸ | CA12 | O43570 | 2/20 | 0.67 |
| ▸ | CA7 | P43166 | 2/20 | 0.67 |
| ▸ | CA9 | Q16790 | 2/20 | 0.67 |
| ▸ | CA14 | Q9ULX7 | 2/20 | 0.67 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.67 |
| ▸ | TP53 | P04637 | 1/20 | 0.60 |
| ▸ | MAPT | P10636 | 4/20 | 0.59 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.59 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.59 |
| ▸ | RAB9A | P51151 | 2/20 | 0.59 |
| ▸ | CASP3 | P42574 | 1/20 | 0.59 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.59 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.59 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.59 |
| ▸ | LOXL2 | Q9Y4K0 | 1/20 | 0.57 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.57 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.57 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Terephthalic Acid SCHEMBL8811649 | 1.00 | TSHR (0.70) | TSHRCA1CA2CA12CA7 | |
| SCHEMBL27555709 | 1.00 | TSHR (0.70) | TSHRCA1CA2CA12CA7 | |
| SCHEMBL63466 | 1.00 | TSHR (0.70) | TSHRCA1CA2CA12CA7 | |
| Terephthalic Acid SCHEMBL18394717 | 1.00 | TSHR (0.70) | TSHRCA1CA2CA12CA7 | |
| SCHEMBL2395112 | 0.98 | TSHR (0.67) | TSHRCA1CA2CA12CA7 | |
| SCHEMBL27860895 | 0.98 | TSHR (0.67) | TSHRCA1CA2CA12CA7 | |
| Methyl Alcohol SCHEMBL29033870 | 0.98 | TSHR (0.67) | TSHRCA1CA2CA12CA7 | |
| SCHEMBL11668494 | 0.98 | TSHR (0.67) | TSHRCA1CA2CA12CA7 | |
| Hydrochloric Acid SCHEMBL296016 | 0.98 | TSHR (0.67) | TSHRCA1CA2CA12CA7 | |
| Terephthalic Acid SCHEMBL27555710 | 0.98 | TSHR (0.67) | TSHRCA1CA2CA12CA7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 27 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3894509-B1 | SELF-CURABLE AND LOW TEMPERATURE CURABLE COATING COMPOSITIONS | EASTMAN CHEM CO (US) | 2024-03-20 | — | — | EP | claimed |
| US-11920050-B2 | Self-curable and low temperature curable coating compositions | EASTMAN CHEMICAL COMPANY (US) | 2024-03-05 | — | — | US | claimed |
| US-20220243090-A1 | SELF-CURABLE AND LOW TEMPERATURE CURABLE COATING COMPOSITIONS | EASTMAN CHEMICAL COMPANY (US) | 2022-08-04 | — | — | US | claimed |
| EP-3894509-A1 | SELF-CURABLE AND LOW TEMPERATURE CURABLE COATING COMPOSITIONS | Eastman Chemical Company (US) | 2021-10-20 | — | — | EP | claimed |
| WO-2020123279-A1 | SELF-CURABLE AND LOW TEMPERATURE CURABLE COATING COMPOSITIONS | EASTMAN CHEMICAL COMPANY (US) | 2020-06-18 | — | — | WO | claimed |
| CN-114516793-B | Method for producing terephthalic acid ester by continuous esterification | 中国科学院大连化学物理研究所 | 2024-05-07 | — | — | CN | disclosed |
| CN-113527666-B | Continuous nylon polymerization method | 成都肆零壹科技有限公司 | 2023-09-12 | — | — | CN | disclosed |
| CN-112390945-B | Continuous nylon polymerization method | 成都肆零壹科技有限公司 | 2022-10-28 | — | — | CN | disclosed |
| CN-113527666-A | Continuous nylon polymerization method | 成都肆零壹科技有限公司 | 2021-10-22 | — | — | CN | disclosed |
| CN-112062950-B | Continuous nylon polymerization process | 成都肆零壹科技有限公司 | 2021-06-29 | — | — | CN | disclosed |
| CN-112390945-A | Continuous nylon polymerization method | 成都肆零壹科技有限公司 | 2021-02-23 | — | — | CN | disclosed |
| CN-112062950-A | Continuous nylon polymerization process | 成都肆零壹科技有限公司 | 2020-12-11 | — | — | CN | disclosed |
| US-6479619-B1 | PRODUCING A PARTIALLY ESTERIFIED ALKALI METAL SULFOISOPHTHALIC ACID IN A GLYCOL; CAN BE MADE IMMEDIATELY PRIOR TO USE; COPOLYMERIZING WITH TEREPHTHALIC ACID AND A GLYCOL TO FORM A POLYESTER | E. I. DU PONT DE NEMOURS AND COMPANY | 2002-11-12 | — | — | US | disclosed |
| WO-2002074834-A1 | SULFOISOPHTHALIC ACID SOLUTION AND PROCESS THEREWITH | E. I. DU PONT DE NEMOURS AND COMPANY (US) | 2002-09-26 | — | — | WO | disclosed |
| US-5738158-A | COPOLYMER OF POLYBUTYLENE TEREPHTHALATE AND POLYOXYALKYLENE DIIMIDE DIACID | THE YOKOHAMA RUBBER CO., LTD. (JP) | 1998-04-14 | — | — | US | disclosed |
| WO-1997013799-A1 | ORIENTABLE, HEAT SETABLE SEMI-CRYSTALLINE COPOLYESTERS | EASTMAN CHEMICAL COMPANY (US) | 1997-04-17 | — | — | WO | disclosed |
| US-5616404-A | Orientable, heat setable semi-crystalline copolyesters | EASTMAN CHEMICAL COMPANY (US) | 1997-04-01 | — | — | US | disclosed |
| WO-1996029357-A1 | USE OF 1,3,5-TRIAZINES WHICH ARE SUBSTITUTED IN THE 2-, 4- AND 6-POSITION OR TAUTOMERS THEREOF FOR CONTROLLING THE CRYSTALLIZATION OF LINEAR POLYESTERS AND/OR POLYESTER POLYOLS AND METHOD FOR THE PREPARATION THEREOF | DESMEPOL B.V. (NL) | 1996-09-26 | — | — | WO | disclosed |
| EP-0119731-B1 | COPOLYESTER OF POLYETHYLENE TEREPHTHALATE, PROCESS FOR MAKING IT AND ITS USE IN PRODUCING MOLDED ARTICLES | ROHM AND HAAS COMPANY (US) | 1989-07-26 | — | — | EP | disclosed |
| US-4508779-A | POLYESTERIMIDE COATINGS | SUMITOMO ELECTRIC INDUSTRIES, LTD. (JP) | 1985-04-02 | — | — | US | disclosed |