Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC7A5 | Q01650 | 1/20 | 0.58 |
| ▸ | SLC1A3 | P43003 | 5/20 | 0.52 |
| ▸ | SLC1A2 | P43004 | 5/20 | 0.52 |
| ▸ | SLC1A1 | P43005 | 4/20 | 0.52 |
| ▸ | GRIK1 | P39086 | 11/20 | 0.50 |
| ▸ | GRIK2 | Q13002 | 5/20 | 0.50 |
| ▸ | GRIA4 | P48058 | 3/20 | 0.50 |
| ▸ | GRIK3 | Q13003 | 3/20 | 0.50 |
| ▸ | GRIK5 | Q16478 | 3/20 | 0.50 |
| ▸ | GRIA2 | P42262 | 2/20 | 0.50 |
| ▸ | GRIA1 | P42261 | 1/20 | 0.50 |
| ▸ | GRM1 | Q13255 | 1/20 | 0.48 |
| ▸ | GRM2 | Q14416 | 1/20 | 0.48 |
| ▸ | LTA4H | P09960 | 1/20 | 0.45 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.44 |
| ▸ | SLC7A11 | Q9UPY5 | 1/20 | 0.44 |
| ▸ | GGT1 | P19440 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL380601 | 1.00 | SLC7A5 (0.58) | SLC7A5SLC1A3SLC1A2SLC1A1GRIK1 | |
| SCHEMBL434919 | 1.00 | SLC7A5 (0.58) | SLC7A5SLC1A3SLC1A2SLC1A1GRIK1 | |
| SCHEMBL21585639 | 1.00 | SLC7A5 (0.58) | SLC7A5SLC1A3SLC1A2SLC1A1GRIK1 | |
| SCHEMBL21585654 | 0.98 | SLC7A5 (0.56) | SLC7A5SLC1A3SLC1A2SLC1A1GRIK1 | |
| SCHEMBL21577845 | 0.85 | SLC7A5 (0.58) | SLC7A5SLC1A3SLC1A2SLC1A1GRIK1 | |
| SCHEMBL21690060 | 0.85 | SLC7A5 (0.58) | SLC7A5SLC1A3SLC1A2SLC1A1GRIK1 | |
| SCHEMBL10212363 | 0.85 | SLC7A5 (0.58) | SLC7A5SLC1A3SLC1A2SLC1A1GRIK1 | |
| SCHEMBL21577850 | 0.81 | SLC7A5 (0.54) | SLC7A5SLC1A3SLC1A2SLC1A1GRIK1 | |
| SCHEMBL18261645 | 0.81 | SLC7A5 (0.54) | SLC7A5SLC1A3SLC1A2SLC1A1GRIK1 | |
| Aspartic Acid SCHEMBL23454434 | 0.80 | SLC7A5 (0.58) | SLC7A5SLC1A3SLC1A2SLC1A1GRIK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 13 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5750555-A | NERVOUS SYSTEM DISORDERS; SKIN DISORDERS; IMMUNOLOGY | GOEDECKE AKTIENGESELLSCHAFT (DE) | 1998-05-12 | — | — | US | claimed |
| EP-1817109-B1 | MIXED-MODAL ANION-EXCHANGE TYPE SEPARATION MATERIAL | MERCK PATENT GMBH (DE) | 2020-02-26 | — | — | EP | disclosed |
| WO-2012012257-A2 | BIVALENT MULTIFUNCTIONAL LIGANDS TARGETING Aβ OLIGOMERS AS TREATMENT FOR ALZHEIMER'S DISEASE | VIRGINIA COMMONWEALTH UNIVERSITY (US) | 2012-01-26 | — | — | WO | disclosed |
| US-7648636-B2 | A chromatographic support including an immobilized ligand which combines an anion-exchange domain comprising an oligocyclic aza compound with endocyclic nitrogen and a non-ionic, second binding domain to allow adjustment of the overall hydrophobicity/hydrophilicity; separation; purification; peptides | MERCK PATENT GMBH (DE) | 2010-01-19 | — | — | US | disclosed |
| EP-2119372-A1 | Aroma compositions and preparations containing N-alpha-beta-alanyl-dipeptides | Symrise GmbH & Co. KG (DE) | 2009-11-18 | — | — | EP | disclosed |
| US-20090104633-A1 | Kit for Highly Sensitive Detection Assays | VYZKUMNY USTAV VETERINARNIHO LEKARSTVI (CZ) | 2009-04-23 | — | — | US | disclosed |
| EP-1971864-A2 | KIT COMPRISING 2,4-DICHLOROPHENOXYACETIC ACD DERIVATIVES AND ANTIBODIES FOR HIGHLY SENSITIVE DETECTION ASSAYS | Forschungszentrum Borstel (DE) | 2008-09-24 | — | — | EP | disclosed |
| US-20080164211-A1 | Mixed-Modal Anion-Exchanged Type Separation Material | MERCK PATENT GMBH (DE) | 2008-07-10 | — | — | US | disclosed |
| EP-1817109-A1 | MIXED-MODAL ANION-EXCHANGE TYPE SEPARATION MATERIAL | Merck Patent GmbH (DE) | 2007-08-15 | — | — | EP | disclosed |
| WO-2007051603-A2 | KIT COMPRISING 2, 4- DICHLOROPHENOXYACETIC ACD DERIVATIVES AND ANTIBODIES FOR HIGHLY SENSITIVE DETECTION ASSAYS | FORSCHUNGSZENTRUM BORSTEL (DE) | 2007-05-10 | — | — | WO | disclosed |
| EP-1693108-A1 | Mixed-modal anion-exchange type separation material | MERCK PATENT GmbH (DE) | 2006-08-23 | — | — | EP | disclosed |
| WO-2006058623-A1 | MIXED-MODAL ANION-EXCHANGE TYPE SEPARATION MATERIAL | MERCK PATENT GMBH (DE) | 2006-06-08 | — | — | WO | disclosed |
| US-5750555-A | NERVOUS SYSTEM DISORDERS; SKIN DISORDERS; IMMUNOLOGY | GOEDECKE AKTIENGESELLSCHAFT (DE) | 1998-05-12 | — | — | US | disclosed |